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7 498 (0,136s)

Result

Wormholes and surface defects in rational ensemble holography

We study wormhole contributions to the bulk path integral in holographic models which are dual to ensembles of rational free boson conformal field theories. We should capture the variance of the ensemble distribution. We sh...

Particles and field physics

  • 2024
  • Jimp
  • Link
Result

Deeper Insight of the Conformational Ensemble of Intrinsically Disordered Proteins

disordered proteins, IDPs, exhibit various structures and conformers, the so-called conformational ensemble, CoE. This study aims to better understand the conformers that make up the IDP ensemble by decom...

Biochemistry and molecular biology

  • 2024
  • Jimp
  • Link
Result

Exploring the impact of alignment media on RDC analysis of phosphorus-containing compounds: a molecular docking approach

approach to generate more accurate conformer ensembles for compounds in the presence that our conformer ensembles outperform moderately the standard, low-energy conformers molecules. Therefore, generating...

Organic chemistry

  • 2023
  • Jimp
  • Link
Result

Interaction kinetics reveal distinct properties of conformational ensembles of three-repeat and four-repeat tau proteins

Tau protein is an intrinsically disordered protein. Its physiological state is best described as a conformational ensemble (CE) of metastable structures interconverting on the local and molecular scale. The monoclonal antibody DC39C...

Biochemistry and molecular biology

  • 2022
  • Jimp
  • Link
Result

Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data

lengths. We offer a detailed picture of the conformational ensemble, current knowledge of the conformations of the full-length nucleocapsid protein the ensemble refinement of SAXS (EROS) method. Our results show t...

Biochemistry and molecular biology

  • 2022
  • Jimp
  • Link
Result

Insights into Unfolded Proteins from the Intrinsic phi/psi Propensities of the AAXAA Host-Guest Series

to examine the conformational makeup of the underlying ensembles giving rise conformational states. One such use is as a baseline for random-coil NMR chemical shifts or no conformational bias. However, there is gr...

BO - Biofyzika

  • 2016
  • Jx
  • Link
Result

Inverse Conformational Selection in Lipid-Protein Binding

, RNA, or viruses. Because lipid headgroup conformational ensembles have not been of conformations? Here, we combine solid-state NMR experiments and molecular dynamics simulations from the NMRlipids Project to resolve the <...

Physical chemistry

  • 2021
  • Jimp
  • Link
Result

A note on ensemble holography for rational tori

We study simple examples of ensemble-averaged holography in free compact boson is primitive (in a sense we explain), the weights in this ensemble average are all equal. In the non-primitive case the ensemble weights are gov...

Particles and field physics

  • 2021
  • Jimp
  • Link
Result

Structural dynamics of propeller loop: towards folding of RNA G-quadruplex

with the unfolded state via an ensemble of cross-like structures (CS) possessing mutually tilted reach the PH conformation from the unfolded state via a conformational diffusion participate in compact coil-like ensembl...

Biochemistry and molecular biology

  • 2018
  • Jimp
  • Link
Result

Accurate Fitting SAXS Curves with NMR Structure Ensembles

for this purpose. Previous implementations of ?ensemble fit? (search for a mix of molecular conformations which matches the SAXS curve) were designed to choose from a huge ensemble......

CE - Biochemie

  • 2015
  • D
  • Link
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