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3 103 (0,167s) •

Projekt

The effect of transmembrane domains of integral proteins on dynamic organisation of the plasma membrane of T lymphocytes (GAP305/11/0459)

. We aim to study the effect of transmembrane domains of four selected proteins of the fluorescent fusion proteins containing the transmembrane domains of the proteins expressed membrane organisation. The ...

EB - Genetika a molekulární biologie

  • 2011 - 2016
    • •
  • 8 812 tis. Kč
    • •
  • 8 812 tis. Kč
    • •
  • GA ČR
Projekt

Signaling and adaptor proteins of leukocyte membrane microdomains (GEMEM/09/E011)

transmembrane adaptors. Elucidation of protein-lipid interactions and protein motifsBiochemical and functional characterization of several novel adaptor proteins and preliminaryexperimental results).2)     Elucida...

EC - Imunologie

  • 2009 - 2012
    • •
  • 6 633 tis. Kč
    • •
  • 6 633 tis. Kč
    • •
  • GA ČR
Projekt

Interferon induced transmembrane proteins as potential targets in cancer therapy (GJ18-23773Y)

. Interferon-induced transmembrane (IFITM) proteins have important antiviral properties the role(s) of IFITM proteins in tumour formation and progression. Based and localization of IFITM proteins in cancer cells an...

Cell biology

  • 2018 - 2022
    • •
  • 5 065 tis. Kč
    • •
  • 5 065 tis. Kč
    • •
  • GA ČR
Projekt

Presentation of results in the 11. International Congress of Virology (PG99163)

The envelope transmembrane glycoprotein gp41 and the core protein p25 assessment of the diagnostic potential. Our results confirm that transmembrane protein into expression vector pET15b. The recombinant protei...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 1999 - 1999
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  • 95 tis. Kč
    • •
  • 45 tis. Kč
    • •
  • MŠMT
Projekt

The yeast cell wall as an extracellular matrix cytoskeleton and cell wall functions (GA204/00/0394)

and cell wall by means of transmembrane proteins of integrin type, into molecular linkers between the cytoskeleton and transmembrane proteins and into interactionbetween these proteins and cell wall polym...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2000 - 2002
    • •
  • 2 072 tis. Kč
    • •
  • 1 372 tis. Kč
    • •
  • GA ČR
Projekt

Function of the transmembrane protein Evi2b in hematopoiesis (GA15-03796S)

is EVI2B. EVI2B encodes a transmembrane protein, is ubiquitously expressed...

FD - Onkologie a hematologie

  • 2015 - 2017
    • •
  • 7 953 tis. Kč
    • •
  • 7 953 tis. Kč
    • •
  • GA ČR
Projekt

Identification of the molecular structure of ligand binding site of melatonin receptor MT2 (GA309/04/0496)

to the seven- transmembrane domain (7TM) receptor superfamily coupled to G-proteins be attributedto the fact that melatonin receptors belong to two distinct classes of proteins, the G-protein coupled receptor fami...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 929 tis. Kč
    • •
  • 2 929 tis. Kč
    • •
  • GA ČR
Projekt

Role of TMEM107 in craniofacial structures development (GA21-05146S)

Transmembrane protein 107 (TMEM107) is localized in the primary cilium and is enriched at the transition zone acting as a key regulator of protein content and composition of the cilium. Mutations in TMEM107 are associated w...

Genetics and heredity (medical genetics to be 3)

  • 2021 - 2023
    • •
  • 10 052 tis. Kč
    • •
  • 9 906 tis. Kč
    • •
  • GA ČR
Projekt

Function-structure relationships between transmembrane adaptor-based signalosomes in mast cells (GAP302/10/1759)

and cytoplasmic components to produce unique signalosomes around transmembrane adaptor proteins. To this aim we will use strains of mice deficient in the expression of various adaptor proteins, and compare detailed propert...

EC - Imunologie

  • 2010 - 2013
    • •
  • 4 998 tis. Kč
    • •
  • 4 998 tis. Kč
    • •
  • GA ČR
Projekt

Mechanisms of the regulation of hematopoiesis and immune response by transmembrane adaptor protein WBP1L (GA21-25527S)

regulated by this protein. The results of this project will help us better understand...

Biochemistry and molecular biology

  • 2021 - 2023
    • •
  • 8 229 tis. Kč
    • •
  • 8 103 tis. Kč
    • •
  • GA ČR
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