Filtry
Single cell techniques in whole genome sequencing of uncultivable pathogenic treponemes (GA17-25455S)
). The goal of this proposal is to develop single cell techniques to perform genomic more than 30 single cell genomes to study intrastrain variability of treponemes.. There are three specific aims...
EE - Mikrobiologie, virologie
- 2017 - 2019 •
- 9 857 tis. Kč •
- 9 566 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2019
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Grantová agentura České republiky
Genome stability in mammalian oocytes and somatic cells (GF21-42225L)
, we focus on the single-strand DNA breaks (SSBs): These are the most common the impact of the abundance of the repair machinery in oocytes and in other cell types, we will directly correlate this with the capacity of the cells<...
Reproductive biology (medical aspects to be 3)
- 2021 - 2024 •
- 6 381 tis. Kč •
- 6 381 tis. Kč •
- GA ČR
Řešení projektu: 1. 10. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Universality of mitotic spindle assembly architecture of the kinetochore and centrosome in the bi-nucleated parasitic protist Giardia intestinalis (GA20-06498S)
The single-celled eukaryotic microorganism Giardia intestinalis is a potent is a unique cell in that it contains two nuclei, which divide in parallel by a rapid semi-open mitosis. Faithful genome segregation is ess...
Parasitology
- 2020 - 2023 •
- 7 089 tis. Kč •
- 7 089 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 30. 6. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Spatiotemporal transcriptome and proteome analysis of α-Synuclein pathology in Parkinson’s disease Identification of cell type-specific vulnerability and tolerance mechanisms (9F24003)
1. Spatiotemporal analysis of neuronal, glial and immune cell responses at transcriptome and proteome level in vulnerable and more resistant brain regions; 2. Multi-omic bioinformatics analysis of spatiotemporal gene and protein expression c...
Other medical science
- 2024 - 2027 •
- 6 633 tis. Kč •
- 6 633 tis. Kč •
- MŠMT
Řešení projektu: 1. 5. 2024 - 30. 4. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Renewal and modernization of the national infrastructure for translational medicine EATRIS-CZ (EH23_015/0008208)
Expansion of services to include the possibility of genomic and proteomic profiling at the level of individual cells by acquiring a mass spectrometer with high sensitivity and high resolution, equipment for genomic sin...
Biochemistry and molecular biology
- 2024 - 2026 •
- 134 688 tis. Kč •
- 34 076 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2024 - 31. 12. 2026
Uznané náklady
Podpora ze státního rozpočtu (25%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Understanding the evolution of amphizoic organisms genomic basis and metabolic potential of organisms capable of living freely and inside hosts (GA25-17373S)
the genomic basis and distinct metabolic capacities of H. inflata, and the levels and directions of gene flow between ecologically distinct populations. We will employ single-cell transcriptomics and whole genome ...
Zoology
- 2025 - 2027 •
- 10 233 tis. Kč •
- 10 233 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The application of new methods of genomic analysis in cases of rare genetic based diseases with negative results of genetic and genomic analyses. (NV19-08-00137)
from standard genetic and genomic analyses. We will benefit from our access and experience with new platforms for whole-genome analysis (NovaSeq), single molecule long genomic information with transcriptome, prote...
Health-related biotechnology
- 2019 - 2023 •
- 14 485 tis. Kč •
- 14 485 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2019 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Zoom in the fish eye & blood molecular evolution of functional adaptations in the deep-sea and freshwater fishes (GA21-31712S)
, and 2) the single-cell RNA sequencing (single-nuclei seq) to further investigate the proposed hypothesis on colour vision in the deep sea. We will further screen genomes-sea fishes, which may enable colour vision...
Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
- 2021 - 2024 •
- 9 953 tis. Kč •
- 9 953 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 30. 6. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Long way to the rumen Evolution and syntrophic symbioses of anaerobic predatory ciliates from the class Litostomatea (GA25-16558S)
in the species Perispira ovum, using single-cell transcriptomics, metagenomics, metabarcoding...
Microbiology
- 2025 - 2027 •
- 7 927 tis. Kč •
- 7 927 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The causes and evolutionary consequences of programmed DNA elimination in songbirds (GA23-07287S)
and genomic approaches including single-cell multiome profiling, we aim to (i) revealMulticellular organisms usually have the same genetic information in all cells of an individual. There is, however, a growing li...
Genetics and heredity (medical genetics to be 3)
- 2023 - 2025 •
- 13 315 tis. Kč •
- 13 315 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2023 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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