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Projekt

The effect of early microbial colonisation on the development of the immune system in children with esophageal atresia. (NW24-07-00042)

Early life microbial colonization influences the reactivity of the immune system throughout human life. The gastrointestinal tract of children with esophageal atresia has not been exposed to the oropharyngeal microbiota or its metabolites before corr...

Paediatrics

  • 2024 - 2027
  • 13 543 tis. Kč
  • 13 543 tis. Kč
  • MZ
Projekt

Role of the esophageal diseases in the ethiology of non-cardiac chest pain (IZ3118)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 600 tis. Kč
  • 556 tis. Kč
  • MZ
Projekt

Host microbiome in relation to Barrett´s esophagus and esophageal adenocarcinoma development (NU20-03-00126)

Along with individual's genetic predisposition, host microbiome is an important factor in etiopathogenesis of gastroesophageal reflux disease (GERD), increasing significantly risk of developing esophagitis (RE), Barrett's esophagus (BE), and esophage...

Cell biology

  • 2020 - 2023
  • 18 202 tis. Kč
  • 18 202 tis. Kč
  • MZ
Projekt

Development of non-invasive diagnosis of extraesophageal symptoms of gastroesophageal reflux disease (NV17-31945A)

Gastroesophageal reflux disease (GERD) is a highly prevalent disease, affecting 10-20% individuals worldwide. It can lead to esophageal and extraesophageal (EER) symptomatology. GERD and EER are two unique, but related disease entities, with differen...

CE - Biochemie

  • 2017 - 2020
  • 9 013 tis. Kč
  • 9 013 tis. Kč
  • MZ
Projekt

Analysis of bile acids as a new, non-invasive method for diagnosing gastroesophageal reflux disease and screening of Barrett’s esophagus. (NU23-08-00303)

Gastroesophageal reflux disease has a high prevalence in general population and it is the most common disease of gastrointestinal tract. It can lead to esophageal and extraesophageal symptomatology, the extraesophageal symptoms being more difficult t...

Gastroenterology and hepatology

  • 2023 - 2026
  • 12 691 tis. Kč
  • 12 691 tis. Kč
  • MZ
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