Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”

Filtry

1 542 (0,08s)

Projekt

The role of glial cells during ischemia/reperfusion and in the course of nervous tissue regeneration. (GA305/06/1316)

Ischemia/reperfusion induces dramatic changes in intracellular Ca2+ concentration ([Ca2+]i) in both neurons and glial cells. These changes are initiated either by Ca2+ entry or by Ca2+ release from intracellular st...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
  • 3 148 tis. Kč
  • 3 148 tis. Kč
  • GA ČR
Projekt

Studies of mitochondrial NA+/CA2+ antiporter (1P05ME796)

characterisation of phanotype of mitichondrial NA+/CA2+ antiporte, characterisation of mitochondrial ATP-sensitive potassium chanel and its role in protection of heart against ischemia......

ED - Fyziologie

  • 2005 - 2008
  • 2 624 tis. Kč
  • 1 312 tis. Kč
  • MŠMT
Projekt

Muscle remodelling on the basis of extracellular matrix seeded with functionally characterized cells. (GA15-09161S)

significance of the Ca2+ homeostasis will be determined in these cells. Optimized cell types for recellularization will be selected on the basis of their phenotypical, Ca2......

ED - Fyziologie

  • 2015 - 2019
  • 5 955 tis. Kč
  • 5 955 tis. Kč
  • GA ČR
Projekt

Influence of thyroid hormones on expression of myofibrillar and Ca2+ transporting proteins (GA304/05/0327)

in regulation of Ca2+ transport systems. The goal of the proposed study is to ascertain whether altered thyroid status influences the expression of MHC isoforms and Ca2 isoforms, sarcoplasmic reticulum Ca2+-ATPase, Na+/

EA - Morfologické obory a cytologie

  • 2005 - 2007
  • 2 528 tis. Kč
  • 2 528 tis. Kč
  • GA ČR
Projekt

The physiology of calcium signalling in human embryonic stem cell-derived neuronal precursors (GAP304/11/2373)

diseases. Ca2+ is an important second messenger participating in many cellular activities; however, to date there has been no clear study investigating the role of Ca2 of NPsin terms of Ca2+ signaling during their propagat...

ED - Fyziologie

  • 2011 - 2013
  • 6 561 tis. Kč
  • 6 561 tis. Kč
  • GA ČR
Projekt

Analysis of intracellular Ca2+ signals in tumor cells pathology of leukemias and lymphomas, in the tumor growth regulation and induction of apoptosis in response to therapy of monoclonal antibodies (NS9670)

intracellular functions are controlled or influenced by changes of intracellular Ca2+ concentration in all cellular systems. In lymphocytes, Ca2+ rises after their activation.It to the therapy with monoclonal antibodies. Ca2

FD - Onkologie a hematologie

  • 2008 - 2011
  • 2 377 tis. Kč
  • 2 350 tis. Kč
  • MZ
Projekt

Pathophysiology of T-type calcium channels in diabetic neuropathy (7AMB15FR015)

of T-type Ca2+ channel / SNAREs interaction. Aim #2: Formation and trafficking of T-type Ca2+ channel / SNAREs complexes. Aim #3: Role of T-type Ca2+ channel / SNARE complexes in vesicular exocytosis. Aim #4. Validation of...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2016
  • 108 tis. Kč
  • 108 tis. Kč
  • MŠMT
Projekt

Mechanism of the melatonin effect on second and third messengers in neonatal rat gonadotrophs (IAA5011705)

involves inhibition of GnRH-induced (Ca2+)i increase. Melatonin blocks Ca2+ mobilization as well as Ca2+ influx through voltage-sensitive channels. Melatonin inhibition of Ca2+ influx through voltage-sensitive cha...

ED - Fyziologie

  • 1997 - 2000
  • 2 595 tis. Kč
  • 1 353 tis. Kč
  • AV ČR
Projekt

Immunopharmacological potential of endoplasmic Ca(2+)-ATPase (SERCA) inhibitors (GA305/07/0061)

in the maintaining Ca2+ homeostasis within the cell is played by a family of sarco/endoplasmic reticulum (ER) Ca2+-ATPases (SERCA). Inhibition of SERCA pumps leads to a release of Ca2+ from ER stores and a concomitant infl...

FR - Farmakologie a lékárnická chemie

  • 2007 - 2011
  • 8 546 tis. Kč
  • 8 546 tis. Kč
  • GA ČR
Projekt

Role of calcium-dependent protein trans-splicing in the virulence of Gram-negative pathogens (GA19-15175S)

-processing module (SPM), which mediates a highly-specific Ca2+-dependent autocatalytic a new isopeptide bond, a process known as "Ca2+-dependent protein trans-splicing". The aim of the project is to determine the role of Ca2

Microbiology

  • 2019 - 2022
  • 9 527 tis. Kč
  • 9 527 tis. Kč
  • GA ČR
  • 1 - 10 z 1 542