Filtry
Effect of metabolic reprogramming of cancer associated fibroblasts on the prognosis of head and neck cancer patients (NU21-03-00223)
Tumor microenvironment consists of various cell populations, for example cancer associated fibroblasts. In many solid tumors, so-called metabolic symbiosis occurs, during which fibroblast-produced lactate serves as a source of carbon for cancer cells...
Cell biology
- 2021 - 2024 •
- 10 043 tis. Kč •
- 10 043 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2021 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Exosomal RNA produced by cancer-associated fibroblasts as a relevant marker in head and neck cancer prognosis (NU20J-08-00018)
Head and neck squamous cell carcinomas (HNSCC) are the fifth most common solid cancer. Unfortunately, no significant improvement has been achieved in HNSCC patient survival due to unpredictable therapy response and therapy resistance which may be sig...
Oncology
- 2020 - 2023 •
- 12 657 tis. Kč •
- 12 657 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2020 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The proteome of extracellular vesicles – the unexplored area of intercellular communication in the tumor microenvironment of head and neck cancer (NU22-03-00202)
Head and neck squamous cell carcinoma (HNSCC) is common and severe solid cancer. Cancer-associated fibroblasts (CAFs) can promote HNSCC progression and therapy resistance by secreting factors contained in exosomes. Exosomes are released from CAFs and...
Otorhinolaryngology
- 2022 - 2025 •
- 10 468 tis. Kč •
- 10 468 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2022 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Dermis replacement in burns and other extensive skin defects (IZ3725)
FP - Ostatní lékařské obory
- 1996 - 1998 •
- 1 107 tis. Kč •
- 1 107 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Development of definitive skin implant based on collagen lattice and autologous cells for the treatment of burn wounds in the animal model. (IZ3093)
FJ - Chirurgie včetně transplantologie
- 1995 - 1997 •
- 380 tis. Kč •
- 380 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1995 - 1. 1. 1997
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer. (2B06077)
DNA in nucleus is wrapped into nucleo-protein structure known as chromatin. Any transaction on DNA requires interactions of chromatin with transcription, replication or gene repair factors. Three independet laboratories with expertise in leukemia/tum...
EB - Genetika a molekulární biologie
- 2006 - 2011 •
- 53 217 tis. Kč •
- 47 631 tis. Kč •
- MŠMT
Řešení projektu: 1. 7. 2006 - 30. 6. 2011
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Identification of new markers for molecular diagnosis of inflammatory and tumor diseases. (2B06155)
The immune system plays a key role for the maintenance of homeostasis. Mechanisms of innate immunity that are mobilized immediately after the contact with infectious agens and determine the character of adaptive immune response are considered as one ...
EC - Imunologie
- 2006 - 2011 •
- 40 489 tis. Kč •
- 36 089 tis. Kč •
- MŠMT
Řešení projektu: 1. 7. 2006 - 30. 6. 2011
Uznané náklady
Podpora ze státního rozpočtu (89%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Recombined artificial skin for treatment of burns (ND5699)
The projekt aims to optimize the authorś original "artificial skin" technique based on a collagen -HA composite and polyurethan membrane, to upgrade it through seeding with fibroblasts and to conduct a randomized clinical study for its evaluation.......
FJ - Chirurgie včetně transplantologie
- 1999 - 2001 •
- 1 874 tis. Kč •
- 1 834 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Ministerstvo zdravotnictví
Markers of mitochondrial dysfunction in presymptomatic and early stages of Huntington‘s disease (NU20-04-00136)
Huntington's disease (HD) is an autosomal dominant hereditary neurodegenerative disorder, manifested mainly by progressive movement disorders, behavioral changes and cognitive impairment. There is no treatment to stop or even cure the disease. The c...
Neurosciences (including psychophysiology)
- 2020 - 2024 •
- 11 878 tis. Kč •
- 11 828 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2020 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular mechanisms of congenital disorders of glycosylation (NV16-31932A)
Congenital Disorders of Glycosylation (CDG) represents a large group of severe inherited metabolic diseases that are caused by impaired biosynthesis of glycoproteins and glycolipids.The complexity of glycosylation pathways determines the occurrence o...
CE - Biochemie
- 2016 - 2020 •
- 11 463 tis. Kč •
- 11 435 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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