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Projekt

Metabolism of selected non-steroidal anti-inflammatory drugs in plants and its environmental consequences (GA14-22593S)

Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the remedies In the Czech Republic. Increasing amount of the NSAIDs and their metabolites in wastewater uptake, distribution and metabolism of selected NSAIDs - ibupro...

CE - Biochemie

  • 2014 - 2016
  • 5 190 tis. Kč
  • 5 190 tis. Kč
  • GA ČR
Projekt

Capsule endoscopy in diagnostics of small bowel mucosal injury induced by nonsteroidal anti-inflammatory drugs (NT13532)

Prospective study is focused on identification of endoscopy, clinical and laboratory small bowel injury markers in long- term NSAID users. The patients with rheumatoid arthritis , osteoarthritis and healthy volunteers will be included into o...

FE - Ostatní obory vnitřního lékařství

  • 2012 - 2015
  • 4 868 tis. Kč
  • 4 868 tis. Kč
  • MZ
Projekt

Synergistic interactions of analgesics with neuropsychotrophic drugs (NL7317)

The principal aim of the project is to find a combination of analgesics with neuropsychotropis drugs which would have significantly greater analgesic effect than the analgesic components alone (in equivalent doses). Major reason for this project is t...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2004
  • 995 tis. Kč
  • 993 tis. Kč
  • MZ
Projekt

The concept of organophosphate-inhibited non-selective cholinesterase reactivators (LUAUS23275)

to in vivo efficacy demonstration testing, one organophosphate from the NSAID group with two reactivators in a model of two NSAIDs and two insecticides.......

Other medical science

  • 2023 - 2027
  • 9 736 tis. Kč
  • 9 736 tis. Kč
  • MŠMT
Projekt

Dual Perfusion of the Human Placenta in vitro for Investigation of Materno-Foetal Kinetics of Drugs (GA305/98/0735)

toinfluence the foetus or the infant ( e. g. NSAIDs and sulfonamides ), will be studied...

FR - Farmakologie a lékárnická chemie

  • 1998 - 2000
  • 1 080 tis. Kč
  • 1 080 tis. Kč
  • GA ČR
Projekt

Biodegradable polyester based nanomaterials as a biotechnological platform for targeted therapy of rheumatoid arthritis (NW25-08-00135)

these immune responses to prevent further joint deterioration. While NSAIDs...

Pharmacology and pharmacy

  • 2025 - 2028
  • 15 511 tis. Kč
  • 15 511 tis. Kč
  • MZ
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