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52 (0,086s) •

Projekt

Concept of liquid biopsy in mapping of microRNA and oncogenic KRAS mutations for early diagnosis and risk assessment of pancreatic cancer. (NU21-07-00247)

characteristics. Analysis of KRAS mutations in circulating tumor DNA in plasma and urine can...

Oncology

  • 2021 - 2024
    • •
  • 13 038 tis. Kč
    • •
  • 13 038 tis. Kč
    • •
  • MZ
Projekt

Development of a New Generation Multiparametric Test for Prediction of Colorectal Neoplasia Recurrence (NV17-31909A)

In years 2017–2020, there will be 200 patients with removed colorectal adenomas >10 mm included. In adenomas high risk areas identified by endoscopist, the histopathology evaluation and molecular examination of intratumoral heterogenity and clonal pr...

FE - Ostatní obory vnitřního lékařství

  • 2017 - 2021
    • •
  • 14 888 tis. Kč
    • •
  • 13 294 tis. Kč
    • •
  • MZ
Projekt

Soil fauna of the cerová vrchovina Portected Landscape Area and the Drienčanský kras Site of Community Importance - a comparative study (7AMB12SK189)

vrchovina Highland and the Driečanský kras Karst. The results of the research...

EG - Zoologie

  • 2012 - 2013
    • •
  • 98 tis. Kč
    • •
  • 98 tis. Kč
    • •
  • MŠMT
Projekt

Electrochemical biosensor for analysis of DNA point mutations in colorectal cancer (NU21-08-00078)

Colorectal cancer (CRC) is one of the most frequent oncological diseases worldwide with rising incidence. Point mutations in certain genes, such as KRAS, BRAF, EGFR or TP53, are one of the key factors in tumor formation, and thus their analy...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2021 - 2024
    • •
  • 7 649 tis. Kč
    • •
  • 7 649 tis. Kč
    • •
  • MZ
Projekt

EGFR and KRAS diagnostics for targeted anticancer therapy (FR-TI1/525)

system for diagnostics of the most frequent activating mutations of the KRAS gene...

FD - Onkologie a hematologie

  • 2009 - 2013
    • •
  • 30 324 tis. Kč
    • •
  • 23 930 tis. Kč
    • •
  • MPO
Projekt

Analysis of EGFR signalling and microRNA expression profiles in prediction of response to anti-EGFR therapy in colorectal cancer patients with wild-type KRAS (NT13860)

In the proposed project we are aiming idetification of the new molecular markers (effector molecules of EGFR signalling, microRNAs) enabling response prediction to anti-EGFR therapy in patients with metastastic colorectal cancer carrying wild-type on...

FD - Onkologie a hematologie

  • 2012 - 2015
    • •
  • 6 455 tis. Kč
    • •
  • 6 455 tis. Kč
    • •
  • MZ
Projekt

Molecular characteristics of borderline ovarian tumors in relation to their biological behavior (NS10566)

(genetic and epigenetic) changes ? mutations of oncogenes KRAS and BRAF, loss...

FK - Gynekologie a porodnictví

  • 2009 - 2011
    • •
  • 4 935 tis. Kč
    • •
  • 4 815 tis. Kč
    • •
  • MZ
Projekt

Lower and higher plants and plant cell cultures as biomarkers for detection of promutagens (OK 156)

EB - Genetika a molekulární biologie

  • 1996 - 1997
    • •
  • 2 532 tis. Kč
    • •
  • 1 000 tis. Kč
    • •
  • MŠMT
Projekt

Molecular biology basis of adenylosuccinate lyase deficiency. (IZ3608)

FG - Pediatrie

  • 1996 - 1998
    • •
  • 2 450 tis. Kč
    • •
  • 2 450 tis. Kč
    • •
  • MZ
Projekt

Molecular Genetic Study in Czech Gaucher Patients Genotype, Phenotype, and Prognosis. (IZ3117)

FG - Pediatrie

  • 1995 - 1998
    • •
  • 1 334 tis. Kč
    • •
  • 1 321 tis. Kč
    • •
  • MZ
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