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5 196 (0,106s)

Projekt

Devices for advanced medical administration of drugs by transdermal route mediated by multifrequency focused ultrasound (FW06010087)

through the skin and its local application with a focus on the application of anti...

Medical engineering

  • 2023 - 2027
  • 21 890 tis. Kč
  • 15 074 tis. Kč
  • TA ČR
Projekt

Pre-clinical development of an acylceramide nanostructured delivery system to rescue the skin barrier in patients with ichthyosis (TH78020002)

into suitable nanostructured systems for targeted delivery into the stratum granulosum/stratum corneum interface, investigate the effects of selected nanoformulations the disrupted lipid synthetic pathways in thes...

Pharmacology and pharmacy

  • 2022 - 2025
  • 5 068 tis. Kč
  • 4 309 tis. Kč
  • TA ČR
Projekt

Interdependencies between Inflammatory Processes and Barrier Lipids in Diseased Skin (GC16-25687J)

The objective of this Czech-German project is a more fundamental understanding of the physiological processes leading to a competent skin barrier and disturbances of these processes in atopic dermatitis. Through a collaboration of research t...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2018
  • 7 313 tis. Kč
  • 7 313 tis. Kč
  • GA ČR
Projekt

Synthesis and structure-activity relationships of skin ceramides and agents targeting them (GAP207/11/0365)

This interdisciplinary project aims at studying ceramides, i.e. the essential components of the skin barrier. The methodical approach combines knowledge from the field of synthetic and physical chemistry of lipids and in vitro dermatology. We will sy...

FR - Farmakologie a lékárnická chemie

  • 2011 - 2013
  • 2 034 tis. Kč
  • 2 034 tis. Kč
  • GA ČR
Projekt

Lipid membrane models – a new tool for studying pathophysiology of skin diseases at a molecular level (GA13-23891S)

of the stratum corneum lipid membranes, and its permeability....

FR - Farmakologie a lékárnická chemie

  • 2013 - 2017
  • 9 734 tis. Kč
  • 9 734 tis. Kč
  • GA ČR
Projekt

Ultralong chain ceramides in membrane models of healthy and diseased skin barrier (GC19-09135J)

In this joint Czech-German project, we propose to investigate the role of ultralong ceramides (both free and in the corneocyte lipid envelope) and long-periodicity lamellar phases in the skin barrier, which are essential components for life on dry la...

Biophysics

  • 2019 - 2021
  • 7 012 tis. Kč
  • 6 957 tis. Kč
  • GA ČR
Projekt

Interpretation and corelation of dynamic and cone penetration test for more effective design traffic structures (TA04031092)

penetration test. The results of the project will be represented by following outputs : - definition of correlative relations between quantities obtained through the dynamic penetration test (the cone penetration ...

JM - Inženýrské stavitelství

  • 2014 - 2017
  • 9 244 tis. Kč
  • 5 955 tis. Kč
  • TA ČR
Projekt

The Evaluation of Penetration of Different Acetylcholinesterase Reactivators through Blood-Brain Barrier (NS9748)

A penetration of different acetylcholinesterase reactivators through the blood-brain barrier will be studied. Firstly, the AChE reactivators will be assessed be means of a novel analytical method in vitro. Based on previous results,...

FR - Farmakologie a lékárnická chemie

  • 2008 - 2010
  • 928 tis. Kč
  • 928 tis. Kč
  • MZ
Projekt

Investigation of radon transport from the foundation soils to the indoor environment through the contact between the building and the subfloor layers (JB204022004)

Proposals of an improvement of techniques of preventive and remedial measures against radon penetration into houses including the Czech National Standard (ČSN 73 0601) and, consequently, proposals of an increase of an effectiveness of state ...

DN - Vliv životního prostředí na zdraví

  • 2004 - 2005
  • 1 600 tis. Kč
  • 1 600 tis. Kč
  • SÚJB
Projekt

Automating the process of penetration tests and increasing the security of JHTP's internal processes (FX04030082_3350)

"As part of the project, in response to a significant increase in cyber attacks, JHTP Corporation will implement two innovations in the process of providing the service that the applicant provides to its to clients through the DLAP platform...

Automation and control systems

  • 2023 - 2024
  • 16 705 tis. Kč
  • 8 268 tis. Kč
  • MPO
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