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Filtry

1 634 (0,072s) •

Projekt

Development and validation of new methods for the assessment of undesirable effects of stomatological materials (IZ3263)

FP - Ostatní lékařské obory

  • 1995 - 1997
    • •
  • 1 538 tis. Kč
    • •
  • 1 180 tis. Kč
    • •
  • MZ
Projekt

In vitro and in vivo study of antimicrobial activity and toxicity of silver nanoparticles, nanocomposites and materials based on silver nanoparticles (GAP304/10/1316)

with antimicrobial activity of silver nanoparticles, but using in vitro methods only.  In vivo size and silver based nanomaterials and in vitro study of their antimicrobial activity and cytotoxicity. Silver nanoparticles s...

EE - Mikrobiologie, virologie

  • 2010 - 2013
    • •
  • 7 711 tis. Kč
    • •
  • 7 711 tis. Kč
    • •
  • GA ČR
Projekt

Anticancer active coordination compounds with multimodal effect (GA21-19060S)

for their in vitro cytotoxicity on a panel of human cancerous and non-malignant cells. Mechanistic aspects of cytotoxicity will be studied by chemical and molecular-biological systems. In the physiological environment, the...

Medicinal chemistry

  • 2021 - 2024
    • •
  • 7 875 tis. Kč
    • •
  • 6 975 tis. Kč
    • •
  • GA ČR
Projekt

Search for novel nucleoside analogs as antivirals against medically important flaviviruses. (LTAUSA18016)

the antiviral activity and cytotoxicity of the synthesized compounds in vitro using the antiviral effect of the nucleosides with a strong in vitro anti-flavivirus activity......

Microbiology

  • 2019 - 2022
    • •
  • 12 123 tis. Kč
    • •
  • 11 329 tis. Kč
    • •
  • MŠMT
Projekt

Generation of dendritic cells in vitro, their characteristics, antigen presenting capacity and potential use in the immunotherapy of minimal residual disease in (NI5669)

Monocyte-derived dendritic cells cultivated in vitro will be pulsed with tumor antigens and cocultivated with autologous lymphocytes in vitro to gain efficient cytotoxic cells directed against tumor cells. The project is fo...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1999 - 2001
    • •
  • 1 362 tis. Kč
    • •
  • 1 362 tis. Kč
    • •
  • MZ
Projekt

Design and preparation of multifunctional magnetic nanoparticles for cancer cell detection (8X20041)

hyperthermia;  Cytotoxicity studies of MNPs;  In vitro magnetic hyperthermia studies...

Other natural sciences

  • 2020 - 2022
    • •
  • 148 tis. Kč
    • •
  • 148 tis. Kč
    • •
  • MŠMT
Projekt

Tumor stress-induced proteins as target structures for cytotoxic cells (IAA5020403)

During the recent period, a number of new findings has been obtained about an alternative pathway for activation of cytotoxic cells that is dependent on the recognition interacting with the key lectin-type receptors of cytotoxic cel...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2008
    • •
  • 4 917 tis. Kč
    • •
  • 4 917 tis. Kč
    • •
  • AV ČR
Projekt

Activation of HIV-Specific CD8+ T Lymphocytes by IL-2 and Histamine Possible Use in Therapy? (NR9032)

Based on the results of the study with patients with hepatitis C and some oncologic diseases we will study in vitro activation of HIV-specific CD8+ T lymphocytes and IFN-gammaHistamine induces activation of cytotoxic CD8+ T Lymphocy...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2006 - 2008
    • •
  • 2 200 tis. Kč
    • •
  • 2 200 tis. Kč
    • •
  • MZ
Projekt

Study of molecular and functional mechanism of novel cytostatics (cyclic polymethinum salts) using human genom-wide screening (GA17-07822S)

comprising determination of cytotoxicity, antiproliferative activity and cellular localization eventually. Screening will consist in determination of the in vitro cytotoxic for cytotoxicity and cell death; 3) Iden...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2019
    • •
  • 9 249 tis. Kč
    • •
  • 8 691 tis. Kč
    • •
  • GA ČR
Projekt

Novel Nano-structured Materials for Elimination of Highly- and Multi-resistant Bacteria and for Overcoming Antibiotic Resistance (GA19-22720S)

and nanostructures. Nanomaterials in combination with antibiotics will be characterized in vitro for their antimicrobial efficacy against resistant pathogens and for their cytotoxicity to mammalian......

Pharmacology and pharmacy

  • 2019 - 2022
    • •
  • 9 896 tis. Kč
    • •
  • 9 885 tis. Kč
    • •
  • GA ČR
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