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2 205 (0,079s)

Projekt

Specific postvaccination immune response against viral pathogens in immunocompromised patients (NU22-05-00402)

receptor antigen-specific cells and its changes in the post-vaccination periodThe response to vaccination fails in some immunocompromised patients. The aim) and in patients with immune mediated inflamatory disease...

Immunology

  • 2022 - 2025
  • 13 035 tis. Kč
  • 13 035 tis. Kč
  • MZ
Projekt

Development of a sublingual mucosal immunization technology platform for needle-free vaccination (7D19003)

Development of sublingual delivery module Development of vaccine formulation In vitro testing of vaccine formulation In vivo testing of vaccine formulation Laboratory analysis of immunity Project IP and management....

Health-related biotechnology

  • 2019 - 2022
  • 20 110 tis. Kč
  • 8 871 tis. Kč
  • MŠMT
Projekt

Significance of T cell response to vaccination against SARS-CoV2 for leukemic patients with weakend immune system (NU22-E-138)

of its deterioration on immune response to vaccination will be assessed. Immune and SARS-CoV-2 specific immunity through quantification of specific effectors of adaptive immunity of haemato-oncologic pati...

Immunology

  • 2022 - 2023
  • 3 780 tis. Kč
  • 3 780 tis. Kč
  • MZ
Projekt

Vaccination efficacy in elderly A protein energy malnutrition model in old mice cohort (8J23AT004)

-energy malnutrition and vaccination / immunization in a cohort of old mice. Long-term to vaccination with a standard vaccine (flu virus) or to immunization with a protein antigen the effectiveness of infl...

Microbiology

  • 2023 - 2024
  • 190 tis. Kč
  • 190 tis. Kč
  • MŠMT
Projekt

Vaccines for induction of mucosal and systemic immunity (IBS5020311)

oral vaccines for mucosal immunization against selected human and veterinary and protective mucosal immune responses that will allow protective oral vaccination. induction of antige-specific humoral and cellular <...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
  • 6 070 tis. Kč
  • 5 365 tis. Kč
  • AV ČR
Projekt

The effect of early microbial colonisation on the development of the immune system in children with esophageal atresia. (NW24-07-00042)

community establishment, which could in turn affect the immune response and vaccine efficacy. We will perform a broad profiling of the immune system to uncover the consequences of delayed colonization on immune sy...

Paediatrics

  • 2024 - 2027
  • 13 866 tis. Kč
  • 13 866 tis. Kč
  • MZ
Projekt

Development of unique vaccines against serious diseases of animals (TH01010837)

1. Development of unique polyvalent vaccines for immunization sows and cows of antigens contained in the vaccine permits to induce an effective protection through one or two applications of the vaccine. That reduce...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2015 - 2016
  • 23 258 tis. Kč
  • 12 450 tis. Kč
  • TA ČR
Projekt

The induction of antiviral immune response after intranasal aplicaton of nanoparticles based vaccine (LTAUSA19003)

The aim of this study is to develop of chitosan-nanoparticles based vaccine against cytomegalovirus for intranasal application and investigation of the immune response on model animals (mice and nonhuman primates) after application ...

Cell biology

  • 2020 - 2022
  • 3 012 tis. Kč
  • 3 012 tis. Kč
  • MŠMT
Projekt

Immunotherapy of chronic myeloid leukemia Development and testing of experimental vaccines in mouse model and immunological study in CML patients (NR9075)

The aim of the project proposed is to test the immunogenicity of genetic and peptide vaccines both individually and in different combinations as well as in combination with chemotherapy. The aim is also to propose a therapeutic vaccine

FD - Onkologie a hematologie

  • 2006 - 2008
  • 20 075 tis. Kč
  • 19 330 tis. Kč
  • MZ
Projekt

Innovative oromucosal immunization (FW03010228)

and comercialization of a nanofiber vaccine for non-invasive immunization against cytomegalovirus testing of the ability of the nanofiber application form to induce an immune response and stabilized immune respons...

Immunology

  • 2021 - 2023
  • 11 895 tis. Kč
  • 8 061 tis. Kč
  • TA ČR
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