Filtry
The study of the bases of congenital disorders of glycosylation (NT12166)
Congenital disorders of glycosylation (CDG) represent a heterogeneous group of metabolic disorders caused by > 40 types of defects in biosynthesis of N- and O of glycosylation disorders will be ch...
FG - Pediatrie
- 2011 - 2015 •
- 7 989 tis. Kč •
- 7 989 tis. Kč •
- MZ
Řešení projektu: 1. 6. 2011 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular mechanisms of congenital disorders of glycosylation (NV16-31932A)
Congenital Disorders of Glycosylation (CDG) represents a large group of severe inherited metabolic diseases that are caused by impaired biosynthesis of glycoproteins and glycolipids.The complexity of glycosylation ...
CE - Biochemie
- 2016 - 2020 •
- 11 463 tis. Kč •
- 11 435 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2016 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Towards a new era for the identification and characterisation of inborn errors of glycosylation (8F19002)
1.Combine omics approaches to solve the most elusive unsolved CDG cases; 2.Develop new ‘omics’ biomarkers for the detection, elucidation and prognosis of the disease; 3.Promote research into the pathophysiology of the disease; 4.Exploit new hypothese...
Social biomedical sciences (includes family planning, sexual health, psycho-oncology, political and social effects of biomedical research)
- 2019 - 2022 •
- 3 843 tis. Kč •
- 3 843 tis. Kč •
- MŠMT
Řešení projektu: 1. 1. 2019 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Molecular genetic causes and biochemical consequences of Congenital disorders of glycosylation (NU22-07-00474)
Congenital Disorders of Glycosylation (CDG syndrome) represent a large group of severe inherited metabolic diseases that are caused by impaired biosynthesis of glycoproteins and glycolipids. Currently there were described m...
Biochemistry and molecular biology
- 2022 - 2025 •
- 12 871 tis. Kč •
- 12 871 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2022 - 31. 12. 2025
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular pathophysiology of erythroid disorders (LH15223)
The project aim is to discover new molecular mechanisms and mutations in selected congenital disorders of erythropoiesis. The project proposal has two stages: a) basic research including study of the molecular mechanisms leading to ...
EB - Genetika a molekulární biologie
- 2015 - 2017 •
- 1 999 tis. Kč •
- 1 999 tis. Kč •
- MŠMT
Řešení projektu: 13. 10. 2015 - 31. 12. 2017
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
Molecular pathophysiology of selected congenital disorders of erythropoiesis (NT13587)
A. Molecular-genetic diagnosis of hemoglobinopathies in Czech population with focus on beta-thalassemic syndromes. B. Cellular and molecular-genetic analysis of selected cases with congenital microcytic anemia due to disrupted iron homeostas...
EB - Genetika a molekulární biologie
- 2012 - 2015 •
- 8 087 tis. Kč •
- 8 087 tis. Kč •
- MZ
Řešení projektu: 1. 4. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Regulation of trafficking and function of the GluN3A-containing NMDA receptors in the mammalian neurons (GA18-04329S)
with various congenital disorders of glycosylation. Our findings will increase our...
Neurosciences (including psychophysiology)
- 2018 - 2020 •
- 6 821 tis. Kč •
- 6 593 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Grantová agentura České republiky
Deciphering the role of Nrf2 in the pathophysiology of phosphomannomutase 2 deficiency (GA22-18235S)
Diseases characterized by cognitive impairment have been widely described to have dysregulated cellular bioenergetics, which is implied as a central causal factor in their pathogenesis. Cognitive deficit is also a dominant feature in the most common ...
Biochemistry and molecular biology
- 2022 - 2024 •
- 6 247 tis. Kč •
- 6 247 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Improvement of molecular diagnostics of congenital adrenal hyperplasia (CAH) (NR9308)
The aim of the project is to improve present DNA diagnostics of congenital adrenal hyperplasia (CAH) in the Czech Republic. By study of CYP21 and CYP21P genes with using of techniques such as MLPA, LR PCR, gene walking, DHPLC and sequencing ...
EB - Genetika a molekulární biologie
- 2007 - 2009 •
- 3 985 tis. Kč •
- 3 736 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (94%)
Poskytovatel: Ministerstvo zdravotnictví
Regulation of NMDA receptor trafficking and function by N-glycosylation (GA14-02219S)
and psychiatric disorders. Although it has been known for more than a decade that NMDA receptors are N-glycosylated, the effect of this modification on the regulation of NMDA, electrophysiology to elucidate i) if the N-glycosyl...
FH - Neurologie, neurochirurgie, neurovědy
- 2014 - 2016 •
- 5 123 tis. Kč •
- 5 123 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2014 - 31. 12. 2016
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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