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6 (0,101s)

Projekt

Mitochondrial optic neuropathies a complex genetic and metabolomic analysis to characterize molecular bases and to identify novel biomarkers (NU22-07-00614)

Mitochondrial diseases are a heterogeneous group of genetic rare disorders that may manifest with a single-organ or multisystemic dysfunction. Ocular involvement, along with myopathy and encephalopathy, figure prominently in the phenotypic spectrum o...

Biochemistry and molecular biology

  • 2022 - 2025
  • 13 769 tis. Kč
  • 13 769 tis. Kč
  • MZ
Projekt

Relation of the structure of the soil saprophagous mite community (Acari Oribatida, Acaridida) and its nutritional biology to the soil rating unit (GA526/07/0393)

Podstata navrhovaného projektu (max. 15 řádek) - anglicky:The soil rating unit has been derived from the abiotic factors and the phytocenological aspect. This project would correlate the mite community structure  and nutritional biology  to ...

EG - Zoologie

  • 2007 - 2009
  • 1 655 tis. Kč
  • 1 655 tis. Kč
  • GA ČR
Projekt

Characterization of the molecular basis of rare genetic diseases of pediatric onset using new methods of genome analysis (NV19-07-00136)

Genomic analysis is a very efficient diagnostic and gene discovery tool. It should ideally be applied in the diagnosis of all patients with rare diseases when the results of clinical, biochemical, metabolic, molecular and cytogenetic analyses do not ...

Human genetics

  • 2019 - 2022
  • 14 718 tis. Kč
  • 14 718 tis. Kč
  • MZ
Projekt

Characterization of the molecular basis of rare genetic diseases of pediatric onset using new methods of genome analysis II. (NU23-07-00281)

Genomic analysis is a very efficient diagnostic and gene discovery tool. It should ideally be applied in the diagnosis of all patients with rare diseases when the results of clinical, biochemical, metabolic, molecular and cytogenetic analyses do not ...

Human genetics

  • 2023 - 2026
  • 14 142 tis. Kč
  • 14 142 tis. Kč
  • MZ
Projekt

Characterization of the molecular basis of rare genetic diseases of pediatric onset using new methods of genome analysis (NV15-28208A)

Rare diseases comprise a group of more than 8000 disorders. Seventy-five per cent of rare diseases affect children, and about 30% of them die before the age of five year. This decrease quality of life for each affected individual, and have a signifi...

EB - Genetika a molekulární biologie

  • 2015 - 2018
  • 16 034 tis. Kč
  • 16 034 tis. Kč
  • MZ
Projekt

Mitochondrial disorders with instability of mitochondrial DNA (NV17-30965A)

Mitochondrial disorders (MD) with estimated incidence 1:4000 are caused by disturbances of oxidative phosphorylation system (OXPHOS) and represent genetically and clinically heterogeneous group of diseases with significant impact on morbidity and mor...

EB - Genetika a molekulární biologie

  • 2017 - 2021
  • 13 003 tis. Kč
  • 12 960 tis. Kč
  • MZ
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