Filtry
Targeted and Improved Alzheimer's Disease Drug Development (TO01000078)
The aim of the project is the development of compounds for the treatment of Alzheimer´s disease (AD). The project will include an approaches of personalized medicine during the development process in the way that novel compounds will be test...
Neurosciences (including psychophysiology)
- 2021 - 2024 •
- 35 184 tis. Kč •
- 26 412 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2021 - 30. 4. 2024
Uznané náklady
Podpora ze státního rozpočtu (75%)
Poskytovatel: Technologická agentura ČR
Neurobehavioral evaluation of potential Alzhemier`s disease drugs (GAP303/12/0611)
The permanent increasing incidence of Alzheimer`s disease represents a wordwile problem that can be partly solved by introducing more effective drugs. The aim inhibitors with better pharmacodynamic features derived from the model
FH - Neurologie, neurochirurgie, neurovědy
- 2012 - 2015 •
- 2 789 tis. Kč •
- 2 789 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The influence of experimental gastrointestinal injury and inflammation on pharmacokinetics of Alzheimer's disease drugs (GA18-13283S)
of drugs used in Alzheimer disease (AD) if patients suffer from gastrointestinal dysfunction (due to ischaemia, drug injury and/or inflammatory bowel disease window of currently available AD drugs and new compound...
Gastroenterology and hepatology
- 2018 - 2022 •
- 10 685 tis. Kč •
- 10 397 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2018 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Grantová agentura České republiky
Development of multi-target drugs for Alzheimer´s disease combination of AChE inhibitor and melatonin derivative (NV15-30954A)
. Such compounds should exert multipotent profile in Alzheimer´s disease treatment by combining activity. Funnel-like drug development process from design and synthesis though, pharmacodynamic and behavioral examination will be appl...
FR - Farmakologie a lékárnická chemie
- 2015 - 2018 •
- 9 036 tis. Kč •
- 9 036 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2015 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Treatment and care of people with Alzheimer's disease - economic burden in the context of the development of new drugs (TL01000300)
The aim of the project is to analyse the development of the number of people with Alzheimer's disease and the related needs for treatment and care in the Czech Republic with a focus on the Hradec Králové Region and the Vysočina Region. The d...
Public administration
- 2018 - 2021 •
- 4 610 tis. Kč •
- 4 146 tis. Kč •
- TA ČR
Řešení projektu: 1. 4. 2018 - 31. 3. 2021
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Technologická agentura ČR
A Microfluidic Platform for Investigating the Mechanism of Action of Alzheimer's Drug Candidates (GF25-15784L)
Protein aggregation lies at the root of Alzheimer's disease, as well as other neurodegenerative disorders such as Huntington’s or Parkinson’s disease. Perturbing the process of aggregation and amyloid formation is a promising concept for the...
Biophysics
- 2025 - 2027 •
- 9 906 tis. Kč •
- 9 906 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Mitochondrial toxicity of tau protein oligomers and its regulation by drugs for Alzheimer's disease (NU23-04-00032)
Alzheimer's disease (AD) is a progressive neurodegenerative disease drugs targeting the primary causes of AD onset and disease progression measurement of regulatory and protective effects of drugs for AD, adjuvants the anti...
Neurosciences (including psychophysiology)
- 2023 - 2026 •
- 6 533 tis. Kč •
- 6 533 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2023 - 31. 12. 2026
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Hybrid structures based on Amiridine as potential multitarget drugs for Alzheimer's disease treatment (GC20-29633J)
Amiridine is anticholinesterase drug used in Russia for treatment of Alzheimer´s disease and a number of other neurological disorders., It is an inhibitor of AChE and BChE, it restores fatty acid and phospholipid metabolism, normali...
Pharmacology and pharmacy
- 2020 - 2022 •
- 4 809 tis. Kč •
- 4 809 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2020 - 31. 12. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Dually acting cognitive enhancers for palliative treatment of Alzheimer´s disease (NU20-08-00296)
Alzheimer´s disease (AD) and other neurodegenerative diseases leading to dementia represent a serious health, social and economic problem symptomatologically manifesting as cognitive disorder and dementia. Currently available treatment and n...
Pharmacology and pharmacy
- 2020 - 2023 •
- 16 485 tis. Kč •
- 16 485 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2020 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Novel inhibitors of acetylcholinesterase derived from 7-MEOTA - potential Alzheimer´s disease drugs (GAP303/11/1907)
and there is demand for novel drugs suitable for its treatment.The main aim of this project derived from 7-MEOTA as potential AD drugs. Synthesized AChE inhibitors will be tested of AChE inhibitors, antioxidant evaluation of novel ...
FR - Farmakologie a lékárnická chemie
- 2011 - 2015 •
- 10 402 tis. Kč •
- 10 402 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2011 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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