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587 (0,078s) •

Projekt

Cell of origin, clonal haematopoiesis and leukaemic clone evolution treatment implications in childhood haematological malignancies (NW24-07-00264)

and investigate this process in a group of paediatric haematological malignancies. The aim and malignancy, and their role in eventual disease recurrence. We will describe these mechanisms in a selected subtypes of...

Paediatrics

  • 2024 - 2027
    • •
  • 18 362 tis. Kč
    • •
  • 18 362 tis. Kč
    • •
  • MZ
Projekt

Expression pattern of WT1 gene isoforms and mutational status as a new pathogenetic and diagnostic marker in paediatric haematological malignancies (NS10488)

WT1 gene is potentially an important marker with hematological malignancies. Its role in malignant and normal cells is presumably influenced by the expression will compare theexpression patterns of malignant cells with the ...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 5 270 tis. Kč
    • •
  • 5 270 tis. Kč
    • •
  • MZ
Projekt

The role of leptin in the regulation of metabolism and haematopoesis in malignant and nonmalignant haematological diseases (NK5455)

The aim of our project is to study the dynamic changes of serum leptin levels in various types of haematological diseases.The data will be compared with those of age the question whether possibile hyperleptinemia in malignant hemato...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 2 691 tis. Kč
    • •
  • 2 691 tis. Kč
    • •
  • MZ
Projekt

Panel of diagnostic reagents for immfenotypization in haematology and rheumatology (1P05OE188)

development of MoAb against ZAP-70 mark, chronical lymphatic leukemia, elaboration of malignant lymphopropilation, diagnosis of rheumazic diseases......

EI - Biotechnologie a bionika

  • 2005 - 2007
    • •
  • 6 908 tis. Kč
    • •
  • 3 592 tis. Kč
    • •
  • MŠMT
Projekt

Immunological background of haematological malignancies in childhood (NV19-07-00329)

Haematological malignancies usually result from cooperation of at least two acquired genetic aberrations, with secondary aberrations driving the transformation of development of haematological malignancies and poss...

Hematology

  • 2019 - 2022
    • •
  • 8 802 tis. Kč
    • •
  • 8 802 tis. Kč
    • •
  • MZ
Projekt

Modulation od cyclin-dependent kinases in haematological malignancies (GA14-19590S)

agents against haematological malignancies will be generated. In this grant we would...

FD - Onkologie a hematologie

  • 2014 - 2016
    • •
  • 8 568 tis. Kč
    • •
  • 8 568 tis. Kč
    • •
  • GA ČR
Projekt

Development of modular bioinformatics platform for next-generation sequencing data analysis. (TJ02000133)

The main goals of proposed project are (i) establishing a comprehensive capture-based NGS panel for haematological malignancies and (ii) the consequent creation of a versatile bioinformatic tool that enables simultaneous analysis of...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2019 - 2021
    • •
  • 9 745 tis. Kč
    • •
  • 8 093 tis. Kč
    • •
  • TA ČR
Projekt

Leukemic cell dying mechanisms during induction therapy in pre-defined haematological malignancies. (IZ4407)

Leukemic cell dying mechanismus during I induction cytostatic therapy in bone marrow and peripheral blood of patients with primary and secundary acute myeloid leukemias.Discrimination between undenfined cell death,apoptosis and necrosis.......

FD - Onkologie a hematologie

  • 1997 - 1999
    • •
  • 858 tis. Kč
    • •
  • 679 tis. Kč
    • •
  • MZ
Projekt

Risk factors for development of CMV virostatic resistance in the patients after allogeneic stem cell transplantation. (NT13691)

in the patients after HSCT in the Institute of Haematology and Blood Transfusion and Dept. of Paediatric Haematology and Oncology of Motol University Hospital between the years 2002......

EE - Mikrobiologie, virologie

  • 2012 - 2015
    • •
  • 9 734 tis. Kč
    • •
  • 9 734 tis. Kč
    • •
  • MZ
Projekt

Cellular Aging in haematological malignancy (NT14310)

for malignancy....

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 8 570 tis. Kč
    • •
  • 8 511 tis. Kč
    • •
  • MZ
  • 1 - 10 z 587