Filtry
Secondary myelodysplastic syndrom and secondary acute leukemia ethiopathogenetic aspects. Prospective clinical and laboratory study. (IZ1568)
9F - 9
- 1993 - 1995 •
- 375 tis. Kč •
- 750 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1993 - 1. 1. 1995
Uznané náklady
Podpora ze státního rozpočtu (200%)
Poskytovatel: Ministerstvo zdravotnictví
The study of pathogenesis of acute leukemias (AL) with 11q23 chromosomal rearrangement (GA301/01/0489)
The 11q23 chromosomal rearrangement, involving transcription factor MLL, has been implicated in an variety of acute leukemias (AL). The AL with MLL rearrangement are either de-novo or secondary (therapy related) and are associated w...
EB - Genetika a molekulární biologie
- 2001 - 2003 •
- 4 604 tis. Kč •
- 4 604 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
NK cell imunotherapy in leukemias – development and characterization of advanced therapy medicinal product. (NV15-30661A)
Leukemia is malignant disease of hematopoesis. Recently, therapeutic strategies an advanced treatment, leukemias return at considerable percentage of patients or the secondary transplantation are available but there is stil...
FD - Onkologie a hematologie
- 2015 - 2018 •
- 4 309 tis. Kč •
- 4 309 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2015 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Non-random abberant changes in childhood acute leukemias. Cytometric and molecular-genetic studies. (NE7430)
Immunophenotypingof acute leukemias (AL) is an important part of their diagnostics. This projekct will be a continuation of a complex research of childhood AL, which combines the analysis of immunophenotype with molecular-genetic and other t...
FD - Onkologie a hematologie
- 2003 - 2005 •
- 3 155 tis. Kč •
- 3 124 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Novel regulatory mechanisms of transcription factors PU.1 and GATA-1 in leukemogenesis. (GPP301/12/P380)
genes. Production of mature blood elements requires connecting PU.1 with secondary that the mutual antagonistic effects between PU.1 and GATA-1 are involved in leukemia blockade and can thus be used to induce cell differentiation a...
FD - Onkologie a hematologie
- 2012 - 2016 •
- 3 726 tis. Kč •
- 3 726 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 7. 4. 2016
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Composition of immunocompetent cells in targeted therapy in pediatric acute lymphoblastic leukemia and lymphoma (NU23-05-00353)
Leukemia and lymphomas are one of most common pediatric malignancies. There are still patients, who respond poorly and/or suffer from relapse and/or experience) in leukemia/lymphoma of B cell origin have recently become an integral ...
Immunology
- 2023 - 2026 •
- 11 022 tis. Kč •
- 11 022 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2023 - 31. 12. 2026
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular cytogenetic analysis of complex chromosomal aberrations in bone marrow cells of patients with myelodysplastic syndrome (MDS) and/or acute myeloid leukemia (AML) and AND its contribution (NR9227)
Molecular cytogenetic analysis of complex chromosomal aberrations in patients with MDS and AML. Identification of chromosomes and/or chromosomal regions involved in complex karyotypes. Evaluation of the impact of complex rearrangements on prognosis o...
EB - Genetika a molekulární biologie
- 2007 - 2009 •
- 3 054 tis. Kč •
- 2 953 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Ministerstvo zdravotnictví
Transcription regulation of the HOX genes in normal and leukemic hematopoiesis (GAP304/12/2214)
, preleukemic cell clones from secondary ALL and slowly developing leukemia, as wellHomeobox (HOX) genes are conserved transcription factors involved in hematopoiesis. HOX deregulation is present in various types of cancer, most fre...
FD - Onkologie a hematologie
- 2012 - 2018 •
- 13 517 tis. Kč •
- 13 517 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 23. 4. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
The ability of dendritic cells to stimulate the tumor specific immune response in patients with lymphoid malignancies (NR8092)
The ability of intranodally injected dendritic cells, pulsed with tetanus toxm toxoid or apoptotic tumor cells will be studied in 20-40 patients with chronic lymphotic leukemia (CLL) or follicular lymphoma (FL). Humoral, cellular and clinica...
FD - Onkologie a hematologie
- 2004 - 2006 •
- 1 660 tis. Kč •
- 1 513 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (91%)
Poskytovatel: Ministerstvo zdravotnictví
Analysis of the proteome of malignant cells two-dimensional elektrophoresis and mass spectrometry (GA303/01/1445)
Studies of the global protein expression (the proteome) of leukemia cell lines derived from several types of leukemia HL60 (promyelocytic leukemia), HEL (erythroleukemia), K562 (chronic myelogenous leukemia) and th...
CE - Biochemie
- 2001 - 2003 •
- 4 204 tis. Kč •
- 2 925 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (70%)
Poskytovatel: Grantová agentura České republiky
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