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Projekt

Long term molecular follow up of chimerism in bone marrow transplanted patients (NC4918)

Long-term molecular follow up of bone marrow tranplanted patiens-Increasing the detectability of mixed chimerism applied on separated individual cell types.......

FD - Onkologie a hematologie

  • 1998 - 2000
  • 2 892 tis. Kč
  • 2 405 tis. Kč
  • MZ
Projekt

Functional Properties of Chimeric and Natural Acetylcholine Receptors (GA305/93/0591)

ED - Fyziologie

  • 1993 - 1995
  • 6 tis. Kč
  • 12 tis. Kč
  • GA ČR
Projekt

Bone marrow transplantation - Analysis and follow- up of cellular chimerism. (IZ896)

9F - 9

  • 1992 - 1996
  • 880 tis. Kč
  • 1 260 tis. Kč
  • MZ
Projekt

Seed-agnostic miRNA binding site classification (GJ19-10976Y)

are routinely employed to this end. Discovery of chimeric reads (miRNA-target hybrids) show ~60% non canonical binding. Here, we propose the production of deep chimeric will use a modified chimeric read identification meth...

Biochemistry and molecular biology

  • 2019 - 2023
  • 8 750 tis. Kč
  • 8 750 tis. Kč
  • GA ČR
Projekt

The molecular genetic analysis of the candidate genes responsible for cytoplasmic male sterility in Silene vulgaris (ME09035)

Recombination in plant mitochondrial genomes generates chimeric genes. Some products of these genes interfere with mitochondrial (mt) function. As the demand the production of viable pollen. Because chimeric genes responsible for po...

EB - Genetika a molekulární biologie

  • 2009 - 2011
  • 1 410 tis. Kč
  • 1 410 tis. Kč
  • MŠMT
Projekt

Treatment strategy in children with high-risk forms of leukemia using hematopoietic stem cell transplantation (NC6512)

disease and chimerism in transplanted patients could help us to stand-up criteria...

FD - Onkologie a hematologie

  • 2001 - 2003
  • 2 709 tis. Kč
  • 2 702 tis. Kč
  • MZ
Projekt

Synthetic multiepitopic vaccine agains boreliosis intended for veterinary applications (TA01011165)

Development of technology for production, purification and stabilisation of subtypes of recombinant chimeric multiepitopic antigens OspC, OspA, DbpA derived from Borelia burgdorferi. Synthesis of glycolipid antigen (acylated cholesteryl-gala...

FP - Ostatní lékařské obory

  • 2011 - 2014
  • 30 472 tis. Kč
  • 23 463 tis. Kč
  • TA ČR
Projekt

G-domains of elongation factors Tu model proteins for the elucidation of structural elements of thermostability (KJB500520503)

using chimerization and comparative mutagenesis. To elucidate the role of amino acid...

EB - Genetika a molekulární biologie

  • 2005 - 2006
  • 547 tis. Kč
  • 547 tis. Kč
  • AV ČR
Projekt

Genetically modified donor T cells as a universal cell source for the immunotherapy of tumors using T lymphocytes equipped with a chimeric antigen receptor (CAR) (FV40145)

a chimeric antigen receptor (CAR) on their surface that will detect specific cell surface...

Oncology

  • 2019 - 2022
  • 15 604 tis. Kč
  • 10 922 tis. Kč
  • MPO
Projekt

Desensitization and ATP binding site of purinergic P2X receptors (IAA5011408)

and chimeric recombinant P2X subunits assembled in homomeric ionotropic ATP receptors and to explainmesurements on chimeric channels. We will also characterize the native P2X receptor......

ED - Fyziologie

  • 2004 - 2008
  • 3 278 tis. Kč
  • 3 278 tis. Kč
  • AV ČR
  • 1 - 10 z 45