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2 555 (0,093s) •

Projekt

Genomic epidemiology of invasive diseases caused by Streptococcus pyogenes in the Czech Republic (NW25-09-00190)

. Analysis of the WGS data will allow detection of S. pyogenes virulence factor genes the emergence of hypervirulent S. pyogenes sublineages. Combination of WGS data an increase in the number of invasive diseases c...

Microbiology

  • 2025 - 2028
    • •
  • 9 149 tis. Kč
    • •
  • 8 393 tis. Kč
    • •
  • MZ
Projekt

Multidisciplinary approach to identification and analysis of causes and also risk factors of increased mortality in invasive infections caused by Streptococcus pyogenes. (NW25-09-00314)

The increasing trend in mortality and the reduction in time from admission to death for invasive Streptococcus pyogenes infections (STPY) in the period 2020-2024 (41.4%; 3 days) compared to the period 2006-2019 (21.9%, 9.5 days) is worrying ...

Infectious Diseases

  • 2025 - 2028
    • •
  • 15 863 tis. Kč
    • •
  • 15 863 tis. Kč
    • •
  • MZ
Projekt

Molecular surveillance of invasive pneumococcal disease in the Czech Republic, assessment of vaccination strategy and recommendation for update (NV17-29256A)

: collection of S. pneumoniae strains isolated from patients with invasive pneumococcal) of S. pneumoniae directly from clinical specimens of culture-negative patients Variable Analysis), WGS (Whole Genome Sequencing) of selected

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2017 - 2021
    • •
  • 6 516 tis. Kč
    • •
  • 6 195 tis. Kč
    • •
  • MZ
Projekt

Molecular genetic typing of Steptococcus pyogenes strains emm typing (NI7382)

The NRL for Streptococci and Enterococci, the only laboratory skilled in S. pyogenes typing in the Czech Republic, intends to implement the genotyping method - emm typing to replace the labour- intensive and much less effective stan...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2003 - 2005
    • •
  • 3 207 tis. Kč
    • •
  • 1 384 tis. Kč
    • •
  • MZ
Projekt

Optimisation of antimicrobial resistance surveillance and decoding of (novel) mechanisms in clinically important Gram-positive pathogens in the Czech Republic (NW25-09-00172)

of macrolides and lincosamides creating selective pressure for S. pyogenes. We will monitor changes in the prevalence of macrolide and clindamycin (linezolid) resistance in S. pyogenes, which are encoded on mobil...

Microbiology

  • 2025 - 2028
    • •
  • 12 383 tis. Kč
    • •
  • 12 383 tis. Kč
    • •
  • MZ
Projekt

Prognostic significance of soluble interleukin-2 receptors in hairy cell leukemia. (IZ1943)

9F - 9

  • 1994 - 1995
    • •
  • 39 tis. Kč
    • •
  • 78 tis. Kč
    • •
  • MZ
Projekt

Tubuloductal carcinoma as a separate entity of breast cancer. (IZ3617)

9F - 9

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 905 tis. Kč
    • •
  • MZ
Projekt

Whole genome sequencing analysis of selected serotypes of Streptococcus pneumoniae causing invasive disease in the Czech Republic (NU22-09-00433)

the question of how expansive the populations of the selected serotypes of S. pneumoniae of S. pneumoniae of all serotypes studied. The S. pneumoniae serotypes selection of knowledge of the spread of genetic lineages of

Microbiology

  • 2022 - 2025
    • •
  • 7 086 tis. Kč
    • •
  • 6 460 tis. Kč
    • •
  • MZ
Projekt

Study of meningococcal population by the whole genome sequencing method - base for update of vaccination strategy (NV19-09-00319)

The project is focused on the study of meningococcal populations by the whole genome sequencing (WGS) method. The WGS method enables a more accurate differentiation between Neisseria meningitidis isolates in comparison with the conventional sequencin...

Infectious Diseases

  • 2019 - 2022
    • •
  • 7 826 tis. Kč
    • •
  • 7 230 tis. Kč
    • •
  • MZ
Projekt

Molecular epidemiology of invasive meningococcal disease in the Czech Republic. (NV15-34887A)

The objective of this project is to set up the molecular surveillance of invasive meningococcal disease in the Czech Republic to be able to distinguish between vaccine failure and non-coverage by vaccine and to update the vaccination strategy recomm...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2015 - 2018
    • •
  • 6 650 tis. Kč
    • •
  • 6 329 tis. Kč
    • •
  • MZ
  • 1 - 10 z 2 555