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7 180 (0,13s) •

Projekt

Application of combinatorial libraries of affinity carriers for the identificatio of new interactions of the protein-ligand type (IAB4055003)

is needed for the identification of the protein-ligand interaction. This procedure a variety of proteins and ligands. The principe of the method is based on the interaction of mixtures of immobil...

CE - Biochemie

  • 2000 - 2002
    • •
  • 2 242 tis. Kč
    • •
  • 1 384 tis. Kč
    • •
  • AV ČR
Projekt

Visual Analysis of Protein-Ligand Interactions (GC18-18647J)

to ensure their effectiveness for the visual analysis of protein-ligand interactions. to understand protein interactions. Thus, we plan to enable the visual analysis of protein-ligand

Computer hardware and architecture

  • 2018 - 2020
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  • 2 982 tis. Kč
    • •
  • 2 270 tis. Kč
    • •
  • GA ČR
Projekt

Study of WD-protein function in actinomycetes (IAA5020207)

as their function is known, consists in protein-protein interaction and in building up and to analyse PkwA and WdpA (=WD40 proteins) ligand proteins from T. curvata and S responsiblefor specific ...

EB - Genetika a molekulární biologie

  • 2002 - 2005
    • •
  • 3 839 tis. Kč
    • •
  • 3 186 tis. Kč
    • •
  • AV ČR
Projekt

Synthesis of Ligands for Interactions with Tetrameric and Pentameric Proteins (GP14-24880P)

of their interaction with tetrameric and pentameric proteins (like Kv1.3 potassium channels, FocAProteins composed from symmetric units have an important role in biological systems, many of them control the core elements o...

CC - Organická chemie

  • 2014 - 2016
    • •
  • 2 664 tis. Kč
    • •
  • 2 664 tis. Kč
    • •
  • GA ČR
Projekt

Investigation of molecular architecture and molecular interactions of biologically important proteins and their protein domains (VS96141)

, and interactions with specific ligands. In collaboration with other laboratories home of the current project is the preparation of key protein components from selected biological, molecular genetics, recombinant expressio...

EA - Morfologické obory a cytologie

  • 1996 - 2000
    • •
  • 36 562 tis. Kč
    • •
  • 30 374 tis. Kč
    • •
  • MŠMT
Projekt

Utilization of integrative molecular biophysical approaches for the functional studies of human natural killer cell receptors and formation of their complexes with tumour ligands (LTC17065)

interaction affinity, both with soluble receptor/ligand forms and within in vitro cell with soluble proteins, but most importantly we aim for observing these interactions formation is expected. Results regarding r...

BO - Biofyzika

  • 2017 - 2020
    • •
  • 3 751 tis. Kč
    • •
  • 3 751 tis. Kč
    • •
  • MŠMT
Projekt

Development of Electroanalytical Methods for Interaction of Galectins and Glycomimetic Ligands – New Potential Anticancer Drugs (GA23-06115S)

The elucidation of the protein-carbohydrate interactions is essential)electrochemical method suitable for the detection of weak non-covalent protein-carbohydrate interactions. This project is focused on galectins a...

Organic chemistry

  • 2023 - 2025
    • •
  • 8 775 tis. Kč
    • •
  • 8 775 tis. Kč
    • •
  • GA ČR
Projekt

Fundamental Principles of Protein Folding and Protein-Ligand Interactions Revealed by High-Level Quantum Chemical Calculations (GA20-08772S)

in protein structure, design, and protein-ligand interactions. Specifically, we will map and study the so-called protein frustration (strain) of the peptide fragments within the context of the protein...

Physical chemistry

  • 2020 - 2022
    • •
  • 8 433 tis. Kč
    • •
  • 6 555 tis. Kč
    • •
  • GA ČR
Projekt

Controlling structure and function of biomolecules at the molecular scale theory meets experiment (GBP208/12/G016)

)reversible processes for following mutually interconnected problems: i) protein-ligand interactions and in silico design of new ligands that exhibit novel properties, ii)interactions involving protei...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2018
    • •
  • 114 429 tis. Kč
    • •
  • 114 429 tis. Kč
    • •
  • GA ČR
Projekt

Investigation of the signal transduction systems in actinomycetes - the roles of WD-proteins and protein Ser/Thr kinases (GA204/99/0491)

, and vesicularfusion and transport. The function of WD40 repeats themselves in particular proteins, insofar as their function is known, consists in protein-protein interaction (=WD40 protein) ligand

EB - Genetika a molekulární biologie

  • 1999 - 2001
    • •
  • 2 762 tis. Kč
    • •
  • 2 450 tis. Kč
    • •
  • GA ČR
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