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5 573 (0,177s)

Projekt

Intracelular effects of uridin in the treatment of palmar-plantar erythrodyesthesia after long-term fluoropyrimidin administration- in vitro study (NS9786)

The mechanism of uridin intracellular activity in keratinocytes (cell line HaCaT, keratinocytes primary samples) by thymidin phosphorylase (TP) and dihydrogen pyrimidin dehydrogenase (DPD) enzymatic activity will be studied...

FR - Farmakologie a lékárnická chemie

  • 2008 - 2011
  • 2 184 tis. Kč
  • 2 184 tis. Kč
  • MZ
Projekt

Comparison of healing effects of allogeneic keratinocytes c cultured on xenodermis and aquagel on burns and donor sites (IZ4368)

The subject of investigation is a comparison of healing effects of a synthetic dressing Aquagel with a biological dressing composed of human keratinocytes cultured on xenodermis. Healing of donor sites and burns will be studied.......

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
  • 1 247 tis. Kč
  • 1 149 tis. Kč
  • MZ
Projekt

Optimization of application of artificial recombined skin for preventing conversion of deep dermal to full thickness burns (IBS5052312)

We introduced cultivation of human keratinocytes for treatment of burns in collaboratio between the IMG AS CR and the Prague Burn Centre. Later, a recombined artificial skin was developed. It consisted of human keratino...

EI - Biotechnologie a bionika

  • 2003 - 2005
  • 1 657 tis. Kč
  • 1 121 tis. Kč
  • AV ČR
Projekt

Modulation of human skin cell responses to UVA radiation by silymarin components (GA15-10897S)

of silymarin and its components most reliably, only primary cultures of human skin fibroblasts and keratinocytes, or human skin explants will be used. in cosmetic preparations, their photostability and phototoxici...

DN - Vliv životního prostředí na zdraví

  • 2015 - 2017
  • 5 469 tis. Kč
  • 5 469 tis. Kč
  • GA ČR
Projekt

Innovation of treatment of critically burned patients by covering largely meshed autografts with human keratinocytes cultured in vitro on acellular xenomatrix (NS10507)

autologous or allogeneic keratinocytes have been cultured. This biological cover will be applied with keratinocytes facing the wound.......

FJ - Chirurgie včetně transplantologie

  • 2009 - 2011
  • 2 426 tis. Kč
  • 2 426 tis. Kč
  • MZ
Projekt

Glycobiology of human epidermis in normal and pathologic conditions (GA304/04/0171)

and reversed-lectin histochemistry, respectively: The normal human epidermis and cultivated keratinocytes will be used for comparison. The project was encouraged by thefindings.), specific primary anti-lectin antibodies an...

EA - Morfologické obory a cytologie

  • 2004 - 2006
  • 1 692 tis. Kč
  • 1 692 tis. Kč
  • GA ČR
Projekt

Photoprotective effects of natural plant phenolics in vitro and in vivo (GP303/07/P314)

phototoxicity on human keratinocytes and in vivo model for monitoring UVA and UVB skin of Lonicera caerulea L. rich on polyphenols) on UVA/UVB-induced damage to human keratinocytes. The effects of test compounds/e...

CE - Biochemie

  • 2007 - 2009
  • 1 157 tis. Kč
  • 1 157 tis. Kč
  • GA ČR
Projekt

Improved growth of human skin cells on biomimetic nanofibrous matrices for active wound healing (GA17-02448S)

In this Project, the adhesion, growth and phenotypic maturation of human keratinocytes and dermal fibroblasts will be studied in vitro on novel polymeric nanofibrous membranes releasing bioactive amino acids (L-arginine), peptides, ...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2021
  • 10 527 tis. Kč
  • 10 131 tis. Kč
  • GA ČR
Projekt

The use of keratinocytes cultured on polymer support in the treatment of extensive burns and trophic defects - clinical study (ND6340)

The aim of this project is to carry out a large clinical study, that would evaluate application possibilities of keratinocytes cultured on polymer support in the treatment of extensive skin losses and trophic defects. We want to create an op...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
  • 2 288 tis. Kč
  • 2 001 tis. Kč
  • MZ
Projekt

The new method of cultivation and transfer of human keratinocytes on polymer matrice for the treatment of severely burned patients (IZ4399)

The goal of this project is to develop a new method of cultivation (without foreign cells) and transfer subconfluent epidermal grafts on synthetic polymer support. Obtained results will enrich the treatment of extensive skin losses.......

FJ - Chirurgie včetně transplantologie

  • 1997 - 1999
  • 1 580 tis. Kč
  • 1 580 tis. Kč
  • MZ
  • 1 - 10 z 5 573