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Projekt

Nicotine as a protective agent in neurodegenerative disorders - an ontogenetic study (GP305/09/P136)

Our previous experiments and findings of other authors indicate that nicotine, histochemical and neurohistological analysis should reveal the effects of nicotine development of Wistar rats. Effects of nicotine will be analy...

ED - Fyziologie

  • 2009 - 2011
    • •
  • 1 236 tis. Kč
    • •
  • 1 236 tis. Kč
    • •
  • GA ČR
Projekt

Genetic determination of the nicotine dependence and the efficaccy of the nicotine dependence treatment (NT12170)

dependence (nicotinism) and successfulness of treatment of that dependence. Observed will be focused on the potential impact on the efficiency of nicotine dependence treatment predispositions playing a role in nicotinism w...

FP - Ostatní lékařské obory

  • 2011 - 2015
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  • 7 420 tis. Kč
    • •
  • 7 420 tis. Kč
    • •
  • MZ
Projekt

Allosteric modulation of nicotinic receptors (IAA100110501)

We will study the influence of allosteric modulators on nicotinic acetylcholine receptor function. We will concentrate on analysis of physostigmine allosteric action on embryonic and adult mouse muscle nicotinic receptors. Wildtype ...

BO - Biofyzika

  • 2005 - 2008
    • •
  • 1 792 tis. Kč
    • •
  • 1 792 tis. Kč
    • •
  • AV ČR
Projekt

Modulation of striatal-based behavior by beta2-containing nicotinic acetylcholine receptors. A functional and morphological approach. (8J21FR022)

Aim 1: Characterizing the expression and (sub)cellular localization of beta2-containing nicotinic receptors in individual groups of striatal GABAINs. To this aim, we will use FISH, electron and super resolution microscopy. Aim 2: Identifyin...

Neurosciences (including psychophysiology)

  • 2021 - 2022
    • •
  • 148 tis. Kč
    • •
  • 148 tis. Kč
    • •
  • MŠMT
Projekt

New method for determination of antibodies against nicotinic acetylcholine receptors in patients with myasthenia gravis. (NF4646)

Development of a new non-radioactive method for the determination of antibodies against nicotinic receptors in patients with myasthenia gravis.......

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
    • •
  • 2 482 tis. Kč
    • •
  • 1 723 tis. Kč
    • •
  • MZ
Projekt

Oro-pharyngeal interface mapping gene expression patterns on the germ-layer dynamics during vertebrate primary mouth formation (GA16-23836S)

of the primary mouth, which involves interactions between ectoderm-derived stomodeum and endodermal foregut that lead to a positioning of the mouth opening. However, surprisingly remarkable diversity in modes of vertebrate primary ...

EG - Zoologie

  • 2016 - 2018
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  • 7 430 tis. Kč
    • •
  • 7 382 tis. Kč
    • •
  • GA ČR
Projekt

Interaction of binding sites of nicotinic acetylcholine receptor (GA202/02/1213)

The nicotinic acetylcholine receptor is a model ligand gated cationic channel which is allostericaly coupled with several interacting binding sites. Two agonist interaction of different binding sites of the nicotinic acetylcholine r...

BO - Biofyzika

  • 2002 - 2004
    • •
  • 2 543 tis. Kč
    • •
  • 1 280 tis. Kč
    • •
  • GA ČR
Projekt

Influence of galvanic phenomena (currents,voltage) on the occurence of algesic symptoms in the mouth (NK6285)

Relationship between occurrence of galvanic and voltage and a presence of algic symptoms in mouth.Galvanic currents reading as a first-choice method for discovering lowered tolerance to metals.......

FP - Ostatní lékařské obory

  • 2000 - 2002
    • •
  • 1 528 tis. Kč
    • •
  • 1 528 tis. Kč
    • •
  • MZ
Projekt

Mechanism and possibilities of pharmacological intervention in presynaptic regulation of acetycholine release (GA305/98/0469)

or nicotinic, andwhich are both of several subtypes. We plan to investigate the mechanism of the nicotinic receptor-induced enhancement of ACh release. Special attention will be given to the effects of allosteric modulators of musc...

ED - Fyziologie

  • 1998 - 2000
    • •
  • 2 887 tis. Kč
    • •
  • 2 470 tis. Kč
    • •
  • GA ČR
Projekt

Corrosion of Prosthodontic Materials in the Mouth Cavity (NS9744)

The project is concerned with dermination of the metal ions released from metal and non-metal dental materials into the saliva of the patient by GF-AAS and ICP MS. 15-20 volunteers will keep the dental denture in their mouth for seven days, ...

FF - ORL, oftalmologie, stomatologie

  • 2008 - 2010
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  • 1 259 tis. Kč
    • •
  • 1 259 tis. Kč
    • •
  • MZ
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