A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00007064%3AK01__%2F18%3AN0000003" target="_blank" >RIV/00007064:K01__/18:N0000003 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.fsigenetics.com/article/S1872-4973(17)30200-4/abstract" target="_blank" >http://www.fsigenetics.com/article/S1872-4973(17)30200-4/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/https://doi.org/10.1016/j.fsigen.2017.09.012" target="_blank" >https://doi.org/10.1016/j.fsigen.2017.09.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations

Popis výsledku v původním jazyce

A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low FST values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.

Název v anglickém jazyce

A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations

Popis výsledku anglicky

A collaborative effort was carried out by the Spanish and Portuguese Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG) to promote knowledge exchange between associate laboratories interested in the implementation of indel-based methodologies and build allele frequency databases of 38 indels for forensic applications. These databases include populations from different countries that are relevant for identification and kinship investigations undertaken by the participating laboratories. Before compiling population data, participants were asked to type the 38 indels in blind samples from annual GHEP-ISFG proficiency tests, using an amplification protocol previously described. Only laboratories that reported correct results contributed with population data to this study. A total of 5839 samples were genotyped from 45 different populations from Africa, America, East Asia, Europe and Middle East. Population differentiation analysis showed significant differences between most populations studied from Africa and America, as well as between two Asian populations from China and East Timor. Low FST values were detected among most European populations. Overall diversities and parameters of forensic efficiency were high in populations from all continents.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

10603 - Genetics and heredity (medical genetics to be 3)

Projekt

<a href="/cs/project/VI20162020015" target="_blank" >VI20162020015: Zavedení nových metod identifikace lidského, zvířecího a rostlinného materiálu do forenzní praxe při dokazování trestných činů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Forensic Science International: Genetics

ISSN

1872-4973

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

January

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

18-25

Kód UT WoS článku

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EID výsledku v databázi Scopus

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