Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002450" target="_blank" >RIV/00023001:_____/11:00002450 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/11:10104202

Výsledek na webu

<a href="http://dx.doi.org/10.2500/aap.2011.32.3423" target="_blank" >http://dx.doi.org/10.2500/aap.2011.32.3423</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2500/aap.2011.32.3423" target="_blank" >10.2500/aap.2011.32.3423</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy

Popis výsledku v původním jazyce

The aim of this study was to confirm or refute the difference between efficacy of long-term specific immunotherapy (SIT) with standardized allergen vaccine consisting of six grass pollens (oat grass, orchard grass, fescue, rye grass, timothy grass, and rye) administered either by sublingual or by supralingual route. To investigate clinical and immunologic changes, 51 patients of a previous 1-year double-blind, placebo-controlled, randomized study were enrolled in an open randomized study that continuedover the next 3 years. Sublingual or supralingual immunotherapy (SLIT) was performed in the same way, keeping the drops under or on the tongue, respectively, for 1-2 minutes before swallowing them. Data about symptoms scores and rescue medication intakeduring grass pollen seasons, as well as skin-prick test results, levels of specific IgG, and IgE antibodies were collected after each pollen season. It was clearly shown that both routes of administration were effective, leading to a sign

Název v anglickém jazyce

Both sublingual and supralingual routes of administration are effective in long-term allergen-specific immunotherapy

Popis výsledku anglicky

The aim of this study was to confirm or refute the difference between efficacy of long-term specific immunotherapy (SIT) with standardized allergen vaccine consisting of six grass pollens (oat grass, orchard grass, fescue, rye grass, timothy grass, and rye) administered either by sublingual or by supralingual route. To investigate clinical and immunologic changes, 51 patients of a previous 1-year double-blind, placebo-controlled, randomized study were enrolled in an open randomized study that continuedover the next 3 years. Sublingual or supralingual immunotherapy (SLIT) was performed in the same way, keeping the drops under or on the tongue, respectively, for 1-2 minutes before swallowing them. Data about symptoms scores and rescue medication intakeduring grass pollen seasons, as well as skin-prick test results, levels of specific IgG, and IgE antibodies were collected after each pollen season. It was clearly shown that both routes of administration were effective, leading to a sign

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Allergy and asthma proceedings

ISSN

1088-5412

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

142-150

Kód UT WoS článku

000289321100009

EID výsledku v databázi Scopus

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