Slow QT interval adaptation to heart rate changes in normal ambulatory subjects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002515" target="_blank" >RIV/00023001:_____/11:00002515 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1542-474X.2011.00420.x" target="_blank" >http://dx.doi.org/10.1111/j.1542-474X.2011.00420.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1542-474X.2011.00420.x" target="_blank" >10.1111/j.1542-474X.2011.00420.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Slow QT interval adaptation to heart rate changes in normal ambulatory subjects

Popis výsledku v původním jazyce

Method: Multiple models of QT dependence on HR were tested in 2 independent populations. Holter recordings were analyzed in population A (healthy volunteers, n = 14, 6 males, age 26.9 +/- 12.3 yr). The hypotheses generated in population A were tested inan independent group population B, healthy volunteers, n = 15, 9 males, age 52.9 +/- 15.6 yr). Linear models of QT interval dependence on a weighted average of RR intervals in the preceding 3 minutes were compared to models based on the immediately preceding RR interval (instantaneous HR). Results: In population A, linear models based on RR intervals over the preceding minute performed better than the best nonlinear model based on the single RR interval immediately preceding the QT interval. Linear models including HR values preceding the QT interval by more than 60 s further improved model fit. This model hierarchy was confirmed in population B. Linear formula for QT correction based on exponential decay of HR effect with 60 s time con

Název v anglickém jazyce

Slow QT interval adaptation to heart rate changes in normal ambulatory subjects

Popis výsledku anglicky

Method: Multiple models of QT dependence on HR were tested in 2 independent populations. Holter recordings were analyzed in population A (healthy volunteers, n = 14, 6 males, age 26.9 +/- 12.3 yr). The hypotheses generated in population A were tested inan independent group population B, healthy volunteers, n = 15, 9 males, age 52.9 +/- 15.6 yr). Linear models of QT interval dependence on a weighted average of RR intervals in the preceding 3 minutes were compared to models based on the immediately preceding RR interval (instantaneous HR). Results: In population A, linear models based on RR intervals over the preceding minute performed better than the best nonlinear model based on the single RR interval immediately preceding the QT interval. Linear models including HR values preceding the QT interval by more than 60 s further improved model fit. This model hierarchy was confirmed in population B. Linear formula for QT correction based on exponential decay of HR effect with 60 s time con

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annals of noninvasive electrocardiology

ISSN

1082-720X

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

148-155

Kód UT WoS článku

000289640500006

EID výsledku v databázi Scopus

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