Implantation of left ventricular assist device complicated by undiagnosed thrombophilia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00055978" target="_blank" >RIV/00023001:_____/12:00055978 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461681/" target="_blank" >http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461681/</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Implantation of left ventricular assist device complicated by undiagnosed thrombophilia

Popis výsledku v původním jazyce

A patient with dilated cardiomyopathy and no history of thromboembolic events received a surgically implanted axial-flow left ventricular assist device. After implantation, transesophageal echocardiography revealed a giant thrombus on the lateral and anterior aspects of the left ventricle. The inflow cannula inserted through the apex of the left ventricle was not obstructed, and the device generated satisfactory blood flow. Laboratory screening for thrombophilia showed protein S deficiency, heterozygousfactor V Leiden mutation, and heterozygous MTHFR C667T mutation. During the entire duration of circulatory support no significant suction events were detected, and the patient was listed for heart transplantation. Ventricular assist device implantationcan unmask previously undiagnosed thrombophilia; therefore, it should be necessary to identify thrombophilic patients before cardiac support implantation. (Tex Heart Inst J 2012;39(5):615-7)

Název v anglickém jazyce

Implantation of left ventricular assist device complicated by undiagnosed thrombophilia

Popis výsledku anglicky

A patient with dilated cardiomyopathy and no history of thromboembolic events received a surgically implanted axial-flow left ventricular assist device. After implantation, transesophageal echocardiography revealed a giant thrombus on the lateral and anterior aspects of the left ventricle. The inflow cannula inserted through the apex of the left ventricle was not obstructed, and the device generated satisfactory blood flow. Laboratory screening for thrombophilia showed protein S deficiency, heterozygousfactor V Leiden mutation, and heterozygous MTHFR C667T mutation. During the entire duration of circulatory support no significant suction events were detected, and the patient was listed for heart transplantation. Ventricular assist device implantationcan unmask previously undiagnosed thrombophilia; therefore, it should be necessary to identify thrombophilic patients before cardiac support implantation. (Tex Heart Inst J 2012;39(5):615-7)

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Texas Heart Institute Journal

ISSN

0730-2347

e-ISSN

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Svazek periodika

39

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

615-617

Kód UT WoS článku

000309796700004

EID výsledku v databázi Scopus

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