ADH1B polymorphism, alcohol consumption, and binge drinking in Slavic Caucasians: Results from the Czech HAPIEE Study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00056338" target="_blank" >RIV/00023001:_____/12:00056338 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/75010330:_____/12:00009872
Výsledek na webu
<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1530-0277.2011.01680.x/abstract;jsessionid=635C58139F72D83ED4B147E013B46F0B.d01t04" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1530-0277.2011.01680.x/abstract;jsessionid=635C58139F72D83ED4B147E013B46F0B.d01t04</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1530-0277.2011.01680.x" target="_blank" >10.1111/j.1530-0277.2011.01680.x</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
ADH1B polymorphism, alcohol consumption, and binge drinking in Slavic Caucasians: Results from the Czech HAPIEE Study
Popis výsledku v původním jazyce
Background: Several genetic polymorphisms influence the risk of heavy alcohol consumption but it is not well understood whether the genetic effects are similar in different populations and drinking cultures, nor whether the genetic influences on binge drinking are similar to those seen for alcoholism. Methods: We have analyzed the effect of the Arg47His (rs1229984) variant within the alcohol dehydrogenase (ADH1B) gene on a range of drinking related variables in a large Eastern European Slavic population(Czech HAPIEE study), which recruited random samples of men and women aged 4569 years in 7 Czech towns (3,016 males and 3,481 females with complete data). Drinking frequency, annual alcohol intake, prevalence of binge drinking (=100 g in men and =60 g in women at least once a month) and the mean dose of alcohol per occasion were measured by the graduated frequency questionnaire. Alcohol intake in a typical week was used to define heavy drinking (=350 g/wk in men and =210 g in women). Pr
Název v anglickém jazyce
ADH1B polymorphism, alcohol consumption, and binge drinking in Slavic Caucasians: Results from the Czech HAPIEE Study
Popis výsledku anglicky
Background: Several genetic polymorphisms influence the risk of heavy alcohol consumption but it is not well understood whether the genetic effects are similar in different populations and drinking cultures, nor whether the genetic influences on binge drinking are similar to those seen for alcoholism. Methods: We have analyzed the effect of the Arg47His (rs1229984) variant within the alcohol dehydrogenase (ADH1B) gene on a range of drinking related variables in a large Eastern European Slavic population(Czech HAPIEE study), which recruited random samples of men and women aged 4569 years in 7 Czech towns (3,016 males and 3,481 females with complete data). Drinking frequency, annual alcohol intake, prevalence of binge drinking (=100 g in men and =60 g in women at least once a month) and the mean dose of alcohol per occasion were measured by the graduated frequency questionnaire. Alcohol intake in a typical week was used to define heavy drinking (=350 g/wk in men and =210 g in women). Pr
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EB - Genetika a molekulární biologie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Alcoholism-clinical and experimental research
ISSN
0145-6008
e-ISSN
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Svazek periodika
36
Číslo periodika v rámci svazku
6
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
900-905
Kód UT WoS článku
000303388500019
EID výsledku v databázi Scopus
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