Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F12%3A00056344" target="_blank" >RIV/00023001:_____/12:00056344 - isvavai.cz</a>
Výsledek na webu
<a href="http://ajpheart.physiology.org/content/302/1/H349.full.pdf+html" target="_blank" >http://ajpheart.physiology.org/content/302/1/H349.full.pdf+html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1152/ajpheart.00147.2011" target="_blank" >10.1152/ajpheart.00147.2011</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load
Popis výsledku v původním jazyce
Effective arterial elastance(E(A)) is a measure of the net arterial load imposed on the heart that integrates the effects of heart rate(HR), peripheral vascular resistance( PVR), and total arterial compliance(TAC) and is a modulator of cardiac performance. To what extent the change in E(A) during exercise impacts on cardiac performance and aerobic capacity is unknown. We examined E(A) and its relationship with cardiovascular performance in 352 healthy subjects. Subjects underwent rest and exercise gatedscans to measure cardiac volumes and to derive E(A)[end-systolic pressure/stroke volume index(SV)], PVR[MAP/(SV*HR)], and TAC(SV/pulse pressure). E(A) varied with exercise intensity: the Delta E(A) between rest and peak exercise along with its determinants, differed among individuals and ranged from -44% to +149%, and was independent of age and sex. Individuals were separated into 3 groups based on their Delta E(A)I. Individuals with the largest increase in Delta E(A)(group 3;Delta E(A)
Název v anglickém jazyce
Use of the Frank-Starling mechanism during exercise is linked to exercise-induced changes in arterial load
Popis výsledku anglicky
Effective arterial elastance(E(A)) is a measure of the net arterial load imposed on the heart that integrates the effects of heart rate(HR), peripheral vascular resistance( PVR), and total arterial compliance(TAC) and is a modulator of cardiac performance. To what extent the change in E(A) during exercise impacts on cardiac performance and aerobic capacity is unknown. We examined E(A) and its relationship with cardiovascular performance in 352 healthy subjects. Subjects underwent rest and exercise gatedscans to measure cardiac volumes and to derive E(A)[end-systolic pressure/stroke volume index(SV)], PVR[MAP/(SV*HR)], and TAC(SV/pulse pressure). E(A) varied with exercise intensity: the Delta E(A) between rest and peak exercise along with its determinants, differed among individuals and ranged from -44% to +149%, and was independent of age and sex. Individuals were separated into 3 groups based on their Delta E(A)I. Individuals with the largest increase in Delta E(A)(group 3;Delta E(A)
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FA - Kardiovaskulární nemoci včetně kardiochirurgie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NS10497" target="_blank" >NS10497: Metabolické faktory ovlivňující progresi chronického srdečního selhání</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
American journal of physiology: Heart and circulatory physiology
ISSN
0363-6135
e-ISSN
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Svazek periodika
302
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
10
Strana od-do
"H349"-"H358"
Kód UT WoS článku
000298643800035
EID výsledku v databázi Scopus
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