Lack of an association between left-handedness and APOE polymorphism in a large sample of adults: Results of the Czech HAPIEE study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F13%3A00058600" target="_blank" >RIV/00023001:_____/13:00058600 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/75010330:_____/13:00010156

Výsledek na webu

<a href="http://www.tandfonline.com/doi/abs/10.1080/1357650X.2012.715164?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#.UihPCp1IuxA" target="_blank" >http://www.tandfonline.com/doi/abs/10.1080/1357650X.2012.715164?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed#.UihPCp1IuxA</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/1357650X.2012.715164" target="_blank" >10.1080/1357650X.2012.715164</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lack of an association between left-handedness and APOE polymorphism in a large sample of adults: Results of the Czech HAPIEE study

Popis výsledku v původním jazyce

An association between APOE genotype and left-handedness has been previously reported. We examined whether such association exists in a population sample of 4438 unrelated Caucasian adults aged 45-69 years (2022 males and 2416 females). Left-handedness was based on self-reported left-hand dominance for writing (prevalence 4.9%) and on consistently higher left-hand grip strength in two repeated measurements (prevalence 12.2%). Individuals with higher left hand grip strength were seven times more likely to be self-reported left handers (p<.0001, chí(2) 159.7, 2 df). There were no differences in the proportion of self-reported left-handedness (p=.828, chí(2) 2.1, 5 df) or higher grip strength in left hand (p=.557, chí(2) 3.9, 5 df) between APOE genotypes.The lack of association was similar in both genders and did not differ by age group. The results suggest that left-handedness in adults is not related to APOE genotype.

Název v anglickém jazyce

Lack of an association between left-handedness and APOE polymorphism in a large sample of adults: Results of the Czech HAPIEE study

Popis výsledku anglicky

An association between APOE genotype and left-handedness has been previously reported. We examined whether such association exists in a population sample of 4438 unrelated Caucasian adults aged 45-69 years (2022 males and 2416 females). Left-handedness was based on self-reported left-hand dominance for writing (prevalence 4.9%) and on consistently higher left-hand grip strength in two repeated measurements (prevalence 12.2%). Individuals with higher left hand grip strength were seven times more likely to be self-reported left handers (p<.0001, chí(2) 159.7, 2 df). There were no differences in the proportion of self-reported left-handedness (p=.828, chí(2) 2.1, 5 df) or higher grip strength in left hand (p=.557, chí(2) 3.9, 5 df) between APOE genotypes.The lack of association was similar in both genders and did not differ by age group. The results suggest that left-handedness in adults is not related to APOE genotype.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Laterality

ISSN

1357-650X

e-ISSN

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Svazek periodika

18

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

513-519

Kód UT WoS článku

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EID výsledku v databázi Scopus

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