Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F14%3A00059031" target="_blank" >RIV/00023001:_____/14:00059031 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.sciencedirect.com/science/article/pii/S0140673614611764" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0140673614611764</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/S0140-6736(14)61176-4" target="_blank" >10.1016/S0140-6736(14)61176-4</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial
Popis výsledku v původním jazyce
Background An increasing number of patients with heart failure receive implantable cardioverter-defibrillators (ICDs) or cardiac resynchronisation defibrillators (CRT-Ds) with telemonitoring function. Early detection of worsening heart failure, or upstream factors predisposing to worsening heart failure, by implant-based telemonitoring might enable pre-emptive intervention and improve outcomes, but the evidence is weak. We investigated this possibility in IN-TIME, a clinical trial. Findings We enrolled716 patients, of whom 664 were randomly assigned (333 to telemonitoring, 331 to control). Mean age was 65.5 years and mean ejection fraction was 26%. 285 (43%) of patients had NYHA functional class II and 378 (57%) had NYHA class III. Most patients received CRT-Ds (390; 58.7%). At 1 year, 63 (18.9%) of 333 patients in the telemonitoring group versus 90 (27.2%) of 331 in the control group (p=0.013) had worsened composite score (odds ratio 0.63, 95% CI 0.43-0.90). Ten versus 27 patients di
Název v anglickém jazyce
Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial
Popis výsledku anglicky
Background An increasing number of patients with heart failure receive implantable cardioverter-defibrillators (ICDs) or cardiac resynchronisation defibrillators (CRT-Ds) with telemonitoring function. Early detection of worsening heart failure, or upstream factors predisposing to worsening heart failure, by implant-based telemonitoring might enable pre-emptive intervention and improve outcomes, but the evidence is weak. We investigated this possibility in IN-TIME, a clinical trial. Findings We enrolled716 patients, of whom 664 were randomly assigned (333 to telemonitoring, 331 to control). Mean age was 65.5 years and mean ejection fraction was 26%. 285 (43%) of patients had NYHA functional class II and 378 (57%) had NYHA class III. Most patients received CRT-Ds (390; 58.7%). At 1 year, 63 (18.9%) of 333 patients in the telemonitoring group versus 90 (27.2%) of 331 in the control group (p=0.013) had worsened composite score (odds ratio 0.63, 95% CI 0.43-0.90). Ten versus 27 patients di
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FA - Kardiovaskulární nemoci včetně kardiochirurgie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Lancet
ISSN
0140-6736
e-ISSN
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Svazek periodika
384
Číslo periodika v rámci svazku
9943
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
8
Strana od-do
583-590
Kód UT WoS článku
000340573300030
EID výsledku v databázi Scopus
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