Clinical value of assessment of left atrial late gadolinium enhancement in patients undergoing ablation of atrial fibrillation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F15%3A00059213" target="_blank" >RIV/00023001:_____/15:00059213 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023884:_____/15:#0007171

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0167527314022141#" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0167527314022141#</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2014.11.072" target="_blank" >10.1016/j.ijcard.2014.11.072</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Clinical value of assessment of left atrial late gadolinium enhancement in patients undergoing ablation of atrial fibrillation

Popis výsledku v původním jazyce

Background: Left atrial (LA) fibrosis begets atrial fibrillation (AF). Cardiovascular magnetic resonance (CMR) using the late gadolinium enhancement (LGE) technique might visualize the LA fibrosis and thus help to choose an appropriate strategy for treatment of AF. In this regard, we investigated whether the extent of preablation LA LGE would predict AF recurrence after ablation in a non-selected patient population. Methods: CMR was performed in 95 patients before radiofrequency ablation of AF. An interpretable scan was available in 73 patients (age, 59 +/- 8 years; men, 71%; persistent/paroxysmal AF, 55/45%). The extent of LA LGE was quantified by three established thresholding techniques. In addition, CMR was used to quantify LA volume and reservoir function. The patients were followed for AF recurrence for 1.3 +/- 0.8 years. Results: The arrhythmia recurred in 29 (40%) of the patients. The extent of LA LGE did not differ between paroxysmal and persistent AF and it did not predict the AF recurrence. Moreover, the extent of LA LGE did not correlate with LA volume, reservoir function and bipolar voltage. Conclusions: Our data indicate a limited value of a routine assessment of LA LGE before ablation of AF. Further experimental and clinical researches should be done before applying the method to a wide clinical practice. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

Název v anglickém jazyce

Clinical value of assessment of left atrial late gadolinium enhancement in patients undergoing ablation of atrial fibrillation

Popis výsledku anglicky

Background: Left atrial (LA) fibrosis begets atrial fibrillation (AF). Cardiovascular magnetic resonance (CMR) using the late gadolinium enhancement (LGE) technique might visualize the LA fibrosis and thus help to choose an appropriate strategy for treatment of AF. In this regard, we investigated whether the extent of preablation LA LGE would predict AF recurrence after ablation in a non-selected patient population. Methods: CMR was performed in 95 patients before radiofrequency ablation of AF. An interpretable scan was available in 73 patients (age, 59 +/- 8 years; men, 71%; persistent/paroxysmal AF, 55/45%). The extent of LA LGE was quantified by three established thresholding techniques. In addition, CMR was used to quantify LA volume and reservoir function. The patients were followed for AF recurrence for 1.3 +/- 0.8 years. Results: The arrhythmia recurred in 29 (40%) of the patients. The extent of LA LGE did not differ between paroxysmal and persistent AF and it did not predict the AF recurrence. Moreover, the extent of LA LGE did not correlate with LA volume, reservoir function and bipolar voltage. Conclusions: Our data indicate a limited value of a routine assessment of LA LGE before ablation of AF. Further experimental and clinical researches should be done before applying the method to a wide clinical practice. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of cardiology

ISSN

0167-5273

e-ISSN

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Svazek periodika

179

Číslo periodika v rámci svazku

Januar 20

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

7

Strana od-do

351-357

Kód UT WoS článku

000346089400097

EID výsledku v databázi Scopus

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