Solid organ transplantation-where we are and how far can we possibly go?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F16%3A00059993" target="_blank" >RIV/00023001:_____/16:00059993 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs10353-016-0403-7" target="_blank" >http://link.springer.com/article/10.1007%2Fs10353-016-0403-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10353-016-0403-7" target="_blank" >10.1007/s10353-016-0403-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Solid organ transplantation-where we are and how far can we possibly go?

Popis výsledku v původním jazyce

Background Solid organ transplants, e. g., kidney, pancreas, and liver, are well-established transplant methods at the Institute for Clinical and Experimental Medicine (IKEM), Czech Republic. Looking at the waiting lists, results, and also population in detail, some patients still suffer. Methods For the described reasons we have introduced some novel transplant methods since the second half of 2011. Kidney patients stay on dialysis; few get the best treatment method, which is live-donor kidney transplantation. Therefore, the live-donor program has been reorganized, kidney paired donation program introduced, miniinvasive donor nephrectomy used in all cases. Some liver patients suffer as well, especially small adults and children, also fulminant liver failure cases and those with multivisceral thrombosis. For these groups of patients we have introduced split-liver transplantation, ABO incompatible (AB0i) liver transplantation, live-donor liver transplantation, auxiliary liver transplantation, and also small bowel/multivisceral transplantation. Results Thanks to the changes, the number of live-donor kidney transplants has increased, the number of liver transplants doubled, many fulminant liver patients survived thanks to AB0i and auxiliary transplantation, and pediatric liver cases waiting time dropped dramatically. The small bowel transplant program started successfully with two multivisceral cases. Conclusion The novel methods and some program changes led to more transplants and also better outcomes. There is still room for further expansion and developments; there are for sure more transplant methods to be introduced. Also, the number of some transplants, e.g., live-donor kidney, still remains low.

Název v anglickém jazyce

Solid organ transplantation-where we are and how far can we possibly go?

Popis výsledku anglicky

Background Solid organ transplants, e. g., kidney, pancreas, and liver, are well-established transplant methods at the Institute for Clinical and Experimental Medicine (IKEM), Czech Republic. Looking at the waiting lists, results, and also population in detail, some patients still suffer. Methods For the described reasons we have introduced some novel transplant methods since the second half of 2011. Kidney patients stay on dialysis; few get the best treatment method, which is live-donor kidney transplantation. Therefore, the live-donor program has been reorganized, kidney paired donation program introduced, miniinvasive donor nephrectomy used in all cases. Some liver patients suffer as well, especially small adults and children, also fulminant liver failure cases and those with multivisceral thrombosis. For these groups of patients we have introduced split-liver transplantation, ABO incompatible (AB0i) liver transplantation, live-donor liver transplantation, auxiliary liver transplantation, and also small bowel/multivisceral transplantation. Results Thanks to the changes, the number of live-donor kidney transplants has increased, the number of liver transplants doubled, many fulminant liver patients survived thanks to AB0i and auxiliary transplantation, and pediatric liver cases waiting time dropped dramatically. The small bowel transplant program started successfully with two multivisceral cases. Conclusion The novel methods and some program changes led to more transplants and also better outcomes. There is still room for further expansion and developments; there are for sure more transplant methods to be introduced. Also, the number of some transplants, e.g., live-donor kidney, still remains low.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

—

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European surgery

ISSN

1682-8631

e-ISSN

—

Svazek periodika

48

Číslo periodika v rámci svazku

Supplement 2

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

5

Strana od-do

"S130"-"S134"

Kód UT WoS článku

000376594600005

EID výsledku v databázi Scopus

—