Impact of body mass index on the outcome of catheter ablation of atrial fibrillation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00077681" target="_blank" >RIV/00023001:_____/19:00077681 - isvavai.cz</a>

Výsledek na webu

<a href="https://heart.bmj.com/content/heartjnl/105/3/244.full.pdf" target="_blank" >https://heart.bmj.com/content/heartjnl/105/3/244.full.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/heartjnl-2018-313490" target="_blank" >10.1136/heartjnl-2018-313490</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of body mass index on the outcome of catheter ablation of atrial fibrillation

Popis výsledku v původním jazyce

Objectives The association between obesity and atrial fibrillation (AF) is well-established. We aimed to evaluate the impact of index body mass index (BMI) on AF recurrence at 12 months following catheter ablation using propensity-weighted analysis. In addition, periprocedural complications and fluoroscopy details were examined to assess overall safety in relationship to increasing BMI ranges. Methods Baseline, periprocedural and follow-up data were collected on consecutive patients scheduled for AF ablation. There were no specific exclusion criteria. Patients were categorised according to baseline BMI in order to assess the outcomes for each category. Results Among 3333 patients, 728 (21.8%) were classified as normal (BMI &lt;25.0 kg/m(2)), 1537 (46.1%) as overweight (BMI 25.5-29.0 kg/m(2)) and 1068 (32.0%) as obese (BMI &gt;= 30.0 kg/m(2)). Procedural duration and radiation dose were higher for overweight and obese patients compared with those with a normal BMI (p=0.002 and p&lt;0.001, respectively). An index BMI &gt;= 30 kg/m(2) led to a 1.2-fold increased likelihood of experiencing recurrent AF at 12-months follow-up as compared with overweight patients (HR 1.223; 95% CI 1.047 to 1.429; p=0.011), while no significant correlation was found between overweight and normal BMI groups (HR 0.954; 95% CI 0.798 to 1.140; p=0.605) and obese versus normal BMI (HR 1.16; 95% CI 0.965 to 1.412; p=0.112). Conclusions Patients with a baseline BMI &gt;= 30 kg/m(2) have a higher recurrence rate of AF following catheter ablation and therefore lifestyle modification to target obesity preprocedure should be considered in these patients.

Název v anglickém jazyce

Impact of body mass index on the outcome of catheter ablation of atrial fibrillation

Popis výsledku anglicky

Objectives The association between obesity and atrial fibrillation (AF) is well-established. We aimed to evaluate the impact of index body mass index (BMI) on AF recurrence at 12 months following catheter ablation using propensity-weighted analysis. In addition, periprocedural complications and fluoroscopy details were examined to assess overall safety in relationship to increasing BMI ranges. Methods Baseline, periprocedural and follow-up data were collected on consecutive patients scheduled for AF ablation. There were no specific exclusion criteria. Patients were categorised according to baseline BMI in order to assess the outcomes for each category. Results Among 3333 patients, 728 (21.8%) were classified as normal (BMI &lt;25.0 kg/m(2)), 1537 (46.1%) as overweight (BMI 25.5-29.0 kg/m(2)) and 1068 (32.0%) as obese (BMI &gt;= 30.0 kg/m(2)). Procedural duration and radiation dose were higher for overweight and obese patients compared with those with a normal BMI (p=0.002 and p&lt;0.001, respectively). An index BMI &gt;= 30 kg/m(2) led to a 1.2-fold increased likelihood of experiencing recurrent AF at 12-months follow-up as compared with overweight patients (HR 1.223; 95% CI 1.047 to 1.429; p=0.011), while no significant correlation was found between overweight and normal BMI groups (HR 0.954; 95% CI 0.798 to 1.140; p=0.605) and obese versus normal BMI (HR 1.16; 95% CI 0.965 to 1.412; p=0.112). Conclusions Patients with a baseline BMI &gt;= 30 kg/m(2) have a higher recurrence rate of AF following catheter ablation and therefore lifestyle modification to target obesity preprocedure should be considered in these patients.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Heart

ISSN

1355-6037

e-ISSN

—

Svazek periodika

105

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

244-250

Kód UT WoS článku

000459806200014

EID výsledku v databázi Scopus

2-s2.0-85054341808