Single mutidrug resistant enterobacteriacae donor-derived infection in four solid organ transplant recipients: a case report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F19%3A00078236" target="_blank" >RIV/00023001:_____/19:00078236 - isvavai.cz</a>

Výsledek na webu

<a href="https://bmcsurg.biomedcentral.com/track/pdf/10.1186/s12893-019-0574-9" target="_blank" >https://bmcsurg.biomedcentral.com/track/pdf/10.1186/s12893-019-0574-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12893-019-0574-9" target="_blank" >10.1186/s12893-019-0574-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Single mutidrug resistant enterobacteriacae donor-derived infection in four solid organ transplant recipients: a case report

Popis výsledku v původním jazyce

Background Bacteraemia of the donor is not considered to be contraindication of organ procurement. On the other hand, infection of solid organ transplant recipients remains to be a major cause of their morbidity and mortality. When using organs from bacteraemic donors, individual risks need to be assessed and the appropriate antibiotic treatment applied. Case presentation In this case series we report several serious donor-derived infectious complications in four out of five recipients of different organs from one single donor in the early posttransplant period. Donor-transmitted multi-drug resistant strains of Escherichia coli and Klebsiella pneumonia was confirmed by both serologic and molecular testing. Conclusions To prevent donor-derived infections, careful microbiological screening followed by targeted antibiotic treatment is essential. Although such complications can never by completely prevented, a high index for potential bacterial infection in organ donors and transplant recipients should be routinely employed.

Název v anglickém jazyce

Single mutidrug resistant enterobacteriacae donor-derived infection in four solid organ transplant recipients: a case report

Popis výsledku anglicky

Background Bacteraemia of the donor is not considered to be contraindication of organ procurement. On the other hand, infection of solid organ transplant recipients remains to be a major cause of their morbidity and mortality. When using organs from bacteraemic donors, individual risks need to be assessed and the appropriate antibiotic treatment applied. Case presentation In this case series we report several serious donor-derived infectious complications in four out of five recipients of different organs from one single donor in the early posttransplant period. Donor-transmitted multi-drug resistant strains of Escherichia coli and Klebsiella pneumonia was confirmed by both serologic and molecular testing. Conclusions To prevent donor-derived infections, careful microbiological screening followed by targeted antibiotic treatment is essential. Although such complications can never by completely prevented, a high index for potential bacterial infection in organ donors and transplant recipients should be routinely employed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BMC surgery

ISSN

1471-2482

e-ISSN

—

Svazek periodika

19

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

"art. no. 111"

Kód UT WoS článku

000480806700001

EID výsledku v databázi Scopus

2-s2.0-85071021021