Short-term trajectories of exercise-induced plasma lipid changes in overweight females, with a focus on HDL-cholesterol

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F21%3A00081011" target="_blank" >RIV/00023001:_____/21:00081011 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.advances.umed.wroc.pl/pdf/2021/30/3/239.pdf" target="_blank" >https://www.advances.umed.wroc.pl/pdf/2021/30/3/239.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17219/acem/129574" target="_blank" >10.17219/acem/129574</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Short-term trajectories of exercise-induced plasma lipid changes in overweight females, with a focus on HDL-cholesterol

Popis výsledku v původním jazyce

Background: Increased levels of plasma lipoproteins are among some of the modifiable risk factors for cardiovascular disease (CVD). Dietary changes and increased physical activity are the most powerful non-pharmacological interventions for achieving optimal plasma lipid levels. Objectives: To investigate the effect of an intensive short-term lifestyle intervention on plasma lipid trajectories in overweight non-diabetic females. Material and methods: A total of 202 healthy overweight (body mass index (BMI) &gt;27.5 kg/m(2)) females underwent an intensive short-term (ten-week) intervention (at least 4 units of one-hour exercise activity weekly at optimal energy intake) aimed at lowering body weight. Plasma lipid (total cholesterol (TC), low-density-lipoprotein cholesterol (LDL-C), high-density-lipoprotein cholesterol (HDL-C), and triglycerides (TG)) levels were examined at baseline and every 2 weeks over the course of the ten-week intervention. Results: There was a significant decrease in BMI (Delta -4.7%, p &lt; 0.001) and body weight (Delta -4.9%, p &lt; 0.001) after the intervention. Positive changes (decreases) in TC (Delta -8%, p &lt; 0.001), TG (Delta -9%, p &lt; 0.001) and LDL-C (Delta -11%, p &lt; 0.001) were observed immediately after 2 weeks, but levels did not decrease further thereafter. In contrast, HDL-C did not increase as expected: after 2 weeks of intervention, we observed a significant decrease of about 6% (p &lt; 0.001) followed by a slow return to baseline values. But even after 10 weeks of intervention, HDL-C values had not reached the values detected at baseline. Conclusions: In overweight females, HDL-C decreased after short-term intensive lifestyle intervention. To confirm the protective effect of increased physical activity, plasma lipids need to be examined over a longer time period.

Název v anglickém jazyce

Short-term trajectories of exercise-induced plasma lipid changes in overweight females, with a focus on HDL-cholesterol

Popis výsledku anglicky

Background: Increased levels of plasma lipoproteins are among some of the modifiable risk factors for cardiovascular disease (CVD). Dietary changes and increased physical activity are the most powerful non-pharmacological interventions for achieving optimal plasma lipid levels. Objectives: To investigate the effect of an intensive short-term lifestyle intervention on plasma lipid trajectories in overweight non-diabetic females. Material and methods: A total of 202 healthy overweight (body mass index (BMI) &gt;27.5 kg/m(2)) females underwent an intensive short-term (ten-week) intervention (at least 4 units of one-hour exercise activity weekly at optimal energy intake) aimed at lowering body weight. Plasma lipid (total cholesterol (TC), low-density-lipoprotein cholesterol (LDL-C), high-density-lipoprotein cholesterol (HDL-C), and triglycerides (TG)) levels were examined at baseline and every 2 weeks over the course of the ten-week intervention. Results: There was a significant decrease in BMI (Delta -4.7%, p &lt; 0.001) and body weight (Delta -4.9%, p &lt; 0.001) after the intervention. Positive changes (decreases) in TC (Delta -8%, p &lt; 0.001), TG (Delta -9%, p &lt; 0.001) and LDL-C (Delta -11%, p &lt; 0.001) were observed immediately after 2 weeks, but levels did not decrease further thereafter. In contrast, HDL-C did not increase as expected: after 2 weeks of intervention, we observed a significant decrease of about 6% (p &lt; 0.001) followed by a slow return to baseline values. But even after 10 weeks of intervention, HDL-C values had not reached the values detected at baseline. Conclusions: In overweight females, HDL-C decreased after short-term intensive lifestyle intervention. To confirm the protective effect of increased physical activity, plasma lipids need to be examined over a longer time period.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Advances in clinical and experimental medicine

ISSN

1899-5276

e-ISSN

—

Svazek periodika

30

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

5

Strana od-do

239-243

Kód UT WoS článku

000636231700002

EID výsledku v databázi Scopus

2-s2.0-85103682947