A patient with pulmonary hypertension waiting for donor lungs during the pandemic : 194 days on extracorporeal life support including 143 days on pulmonary artery to left atrium shunt

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F22%3A00083450" target="_blank" >RIV/00023001:_____/22:00083450 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/22:10436227 RIV/00064203:_____/22:10436227 RIV/00216208:11110/22:10436227 RIV/00216208:11130/22:10436227

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S1600613522000053?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S1600613522000053?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/ajt.16949" target="_blank" >10.1111/ajt.16949</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A patient with pulmonary hypertension waiting for donor lungs during the pandemic : 194 days on extracorporeal life support including 143 days on pulmonary artery to left atrium shunt

Popis výsledku v původním jazyce

Patients with pulmonary hypertension and end-stage lung disease are fraught with high mortality while on a waiting list for lung transplant. With sometimes rapid deterioration they may require veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as an immediate life-saving technique, which is a time-limited solution. The technique of pulmonary artery to left atrium (PA-LA) shunt fitted with an oxygenator enables bridging the patient to transplant for a longer time period. This low-resistance paracorporeal pumpless lung assist device allows for de-adaptation of the right ventricle back to lower afterload before the lung transplantation is carried out. The PA-LA shunt with an oxygenator also conveys a risk of multiple complications with reported median of 10-26 days until transplant. We report a case of pulmonary capillary hemangiomatosis in a 35-year-old female who had to wait for donor lungs during the pandemic of SARS-CoV-2 for 143 days on PA-LA shunt with oxygenator following 51 days on VA-ECMO. The extremely long course associated with multiple complications including three cerebral embolisms, episodes of sepsis and ingrowth of the return cannula into the left ventricular wall gives insight into the limits of this bridging technique.

Název v anglickém jazyce

A patient with pulmonary hypertension waiting for donor lungs during the pandemic : 194 days on extracorporeal life support including 143 days on pulmonary artery to left atrium shunt

Popis výsledku anglicky

Patients with pulmonary hypertension and end-stage lung disease are fraught with high mortality while on a waiting list for lung transplant. With sometimes rapid deterioration they may require veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as an immediate life-saving technique, which is a time-limited solution. The technique of pulmonary artery to left atrium (PA-LA) shunt fitted with an oxygenator enables bridging the patient to transplant for a longer time period. This low-resistance paracorporeal pumpless lung assist device allows for de-adaptation of the right ventricle back to lower afterload before the lung transplantation is carried out. The PA-LA shunt with an oxygenator also conveys a risk of multiple complications with reported median of 10-26 days until transplant. We report a case of pulmonary capillary hemangiomatosis in a 35-year-old female who had to wait for donor lungs during the pandemic of SARS-CoV-2 for 143 days on PA-LA shunt with oxygenator following 51 days on VA-ECMO. The extremely long course associated with multiple complications including three cerebral embolisms, episodes of sepsis and ingrowth of the return cannula into the left ventricular wall gives insight into the limits of this bridging technique.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American journal of transplantation

ISSN

1600-6135

e-ISSN

1600-6143

Svazek periodika

22

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

2094-2098

Kód UT WoS článku

000744081700001

EID výsledku v databázi Scopus

2-s2.0-85122852539