Longitudinal trends in severe dyslipidemia in the Czech population : the Czech MONICA and Czech Post-MONICA study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F23%3A00084126" target="_blank" >RIV/00023001:_____/23:00084126 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/23:10467715 RIV/00064190:_____/23:10001174 RIV/00216208:11110/23:10467715

Výsledek na webu

<a href="https://www.mdpi.com/2308-3425/10/8/328" target="_blank" >https://www.mdpi.com/2308-3425/10/8/328</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcdd10080328" target="_blank" >10.3390/jcdd10080328</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Longitudinal trends in severe dyslipidemia in the Czech population : the Czech MONICA and Czech Post-MONICA study

Popis výsledku v původním jazyce

Background: Severe hypercholesterolemia is associated with an increase in the risk of developing atherosclerotic cardiovascular disease. The aim of this analysis was to assess longitudinal trends in severe dyslipidemia (defined as total cholesterol &gt; 8 mmol/L or LDL-cholesterol &gt; 5 mmol/L) in a representative population sample of the Czech Republic and to analyze the longitudinal trends in the basic characteristics of individuals with severe dyslipidemia. Methods: Seven independent cross-sectional surveys were organized in the Czech Republic to screen for major cardiovascular risk factors (from 1985 to 2015-2018). A total of 20,443 randomly selected individuals aged 25-64 years were examined. Results: The overall prevalence of severe dyslipidemia was 6.6%, with a significant downward trend from the fifth survey onwards (2000/2001). Over the study period of 30+ years, the individuals with severe dyslipidemia became older, increased in BMI, and did not change their smoking habits. Total cholesterol and non-HDL-cholesterol decreased significantly in both sexes throughout the duration of the study. Conclusions: Despite a significant improvement in lipids in the Czech Republic from 1985, substantially contributing to the decline in cardiovascular mortality, the number of individuals with severe dyslipidemia remained high, and in most cases, they were newly detected during our screening examinations and were thus untreated.

Název v anglickém jazyce

Longitudinal trends in severe dyslipidemia in the Czech population : the Czech MONICA and Czech Post-MONICA study

Popis výsledku anglicky

Background: Severe hypercholesterolemia is associated with an increase in the risk of developing atherosclerotic cardiovascular disease. The aim of this analysis was to assess longitudinal trends in severe dyslipidemia (defined as total cholesterol &gt; 8 mmol/L or LDL-cholesterol &gt; 5 mmol/L) in a representative population sample of the Czech Republic and to analyze the longitudinal trends in the basic characteristics of individuals with severe dyslipidemia. Methods: Seven independent cross-sectional surveys were organized in the Czech Republic to screen for major cardiovascular risk factors (from 1985 to 2015-2018). A total of 20,443 randomly selected individuals aged 25-64 years were examined. Results: The overall prevalence of severe dyslipidemia was 6.6%, with a significant downward trend from the fifth survey onwards (2000/2001). Over the study period of 30+ years, the individuals with severe dyslipidemia became older, increased in BMI, and did not change their smoking habits. Total cholesterol and non-HDL-cholesterol decreased significantly in both sexes throughout the duration of the study. Conclusions: Despite a significant improvement in lipids in the Czech Republic from 1985, substantially contributing to the decline in cardiovascular mortality, the number of individuals with severe dyslipidemia remained high, and in most cases, they were newly detected during our screening examinations and were thus untreated.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NV15-27109A" target="_blank" >NV15-27109A: Dlouhodobé trendy hlavních kardiovaskulárních rizikových faktorů a jejich prediktivní hodnota v náhodně vybraném populačním vzorku, Czech post-MONICA</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of cardiovascular development and disease

ISSN

2308-3425

e-ISSN

2308-3425

Svazek periodika

10

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

9

Strana od-do

"art. no. 328"

Kód UT WoS článku

001056814500001

EID výsledku v databázi Scopus

2-s2.0-85169141012