Zinc in dermatology: exploring its emerging role in enhancing botulinum toxin formulations and clinical efficacy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F24%3A00085268" target="_blank" >RIV/00023001:_____/24:00085268 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/1467-3045/46/11/717" target="_blank" >https://www.mdpi.com/1467-3045/46/11/717</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/cimb46110717" target="_blank" >10.3390/cimb46110717</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Zinc in dermatology: exploring its emerging role in enhancing botulinum toxin formulations and clinical efficacy

Popis výsledku v původním jazyce

This literature review provides a novel exploration of zinc’s multifaceted roles in dermatology, with a particular focus on its potential integration into botulinum toxin formulations—an area that remains relatively underexplored in clinical practice. Zinc is widely recognized for its critical functions in skin health, including morphogenesis, regeneration, and protection, and its use in aesthetic medicine offers a unique opportunity for innovation. Specifically, incorporating zinc into botulinum toxin formulations could enhance the efficacy and stability of these treatments. Citation: Foster, L.; Foppiani, J.A.; Xun, H.; Lee, D.; Utz, B.; Hernandez Alvarez, A.; Domingo-Escobar, M.J.; Taritsa, I.C.; Gavlasova, D.; Lee, T.C.; et al. Zinc in Dermatology: Exploring Its Emerging Role in Enhancing Botulinum Toxin Formulations and Clinical Efficacy. Curr. Issues Mol. Biol. 2024, 46, 12088–12098. https:// doi.org/10.3390/cimb46110717 Academic Editor: Sherif T. S. Hassan Received: 14 August 2024 Revised: 23 October 2024 Accepted: 25 October 2024 Published: 28 October 2024 Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). Although zinc has historically been used in topical dermatological products and systemic health interventions, its potential in cosmetic preparations, such as anti-aging therapies or non-invasive aesthetic treatments, remains under-researched. Emerging patents suggest promising formulations combining zinc with botulinum toxin that may improve product stability and extend therapeutic effects. While current studies on oral zinc supplementation present mixed results concerning its ability to prolong botulinum toxin effects, this underscores the need for more rigorous investigation in the realm of aesthetic medicine. Zinc’s well-established role in stabilizing dermatological products, such as sunscreens, and its applications in wound healing and skin regeneration, further highlights its potential for broader therapeutic uses beyond cosmetic applications. This review identifies a critical gapintheliterature and calls for future research to optimize zinc concentrations and delivery methods specifically for aesthetic medical procedures, offering new insights into improving dermatological treatments beyond the scope of traditional cosmetic preparations.

Název v anglickém jazyce

Zinc in dermatology: exploring its emerging role in enhancing botulinum toxin formulations and clinical efficacy

Popis výsledku anglicky

This literature review provides a novel exploration of zinc’s multifaceted roles in dermatology, with a particular focus on its potential integration into botulinum toxin formulations—an area that remains relatively underexplored in clinical practice. Zinc is widely recognized for its critical functions in skin health, including morphogenesis, regeneration, and protection, and its use in aesthetic medicine offers a unique opportunity for innovation. Specifically, incorporating zinc into botulinum toxin formulations could enhance the efficacy and stability of these treatments. Citation: Foster, L.; Foppiani, J.A.; Xun, H.; Lee, D.; Utz, B.; Hernandez Alvarez, A.; Domingo-Escobar, M.J.; Taritsa, I.C.; Gavlasova, D.; Lee, T.C.; et al. Zinc in Dermatology: Exploring Its Emerging Role in Enhancing Botulinum Toxin Formulations and Clinical Efficacy. Curr. Issues Mol. Biol. 2024, 46, 12088–12098. https:// doi.org/10.3390/cimb46110717 Academic Editor: Sherif T. S. Hassan Received: 14 August 2024 Revised: 23 October 2024 Accepted: 25 October 2024 Published: 28 October 2024 Copyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). Although zinc has historically been used in topical dermatological products and systemic health interventions, its potential in cosmetic preparations, such as anti-aging therapies or non-invasive aesthetic treatments, remains under-researched. Emerging patents suggest promising formulations combining zinc with botulinum toxin that may improve product stability and extend therapeutic effects. While current studies on oral zinc supplementation present mixed results concerning its ability to prolong botulinum toxin effects, this underscores the need for more rigorous investigation in the realm of aesthetic medicine. Zinc’s well-established role in stabilizing dermatological products, such as sunscreens, and its applications in wound healing and skin regeneration, further highlights its potential for broader therapeutic uses beyond cosmetic applications. This review identifies a critical gapintheliterature and calls for future research to optimize zinc concentrations and delivery methods specifically for aesthetic medical procedures, offering new insights into improving dermatological treatments beyond the scope of traditional cosmetic preparations.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current issues in molecular biology

ISSN

1467-3037

e-ISSN

1467-3045

Svazek periodika

46

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

11

Strana od-do

12088-12098

Kód UT WoS článku

001364147300001

EID výsledku v databázi Scopus

2-s2.0-85210426401