An isotopic case study of individuals with syphilis from the pathological-anatomical reference collection of the national museum in Prague (Czech Republic, 19th century A.D.)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023272%3A_____%2F19%3A10134357" target="_blank" >RIV/00023272:_____/19:10134357 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/19:10403592

Výsledek na webu

<a href="https://doi.org/10.1016/j.ijpp.2019.04.001" target="_blank" >https://doi.org/10.1016/j.ijpp.2019.04.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijpp.2019.04.001" target="_blank" >10.1016/j.ijpp.2019.04.001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

An isotopic case study of individuals with syphilis from the pathological-anatomical reference collection of the national museum in Prague (Czech Republic, 19th century A.D.)

Popis výsledku v původním jazyce

OBJECTIVE: This paper aims at investigating the possible existence of isotopic offsets in delta13Ccol and delta15Ncol values in relation to tertiary syphilis. MATERIAL: Based on materials from the 19th c. A.D. deriving from the pathological-anatomical reference collection (the Jedlicka collection) of the National Museum in Prague (Czech Republic), a comparative approach of ten individuals with syphilis and nine without the disease was undertaken. METHODS: Bone powder samples were defatted according to the protocol of Liden et al. (1995). Bone collagen was extracted following the protocol of Bocherens et al. (1991). RESULTS: Our results show that individuals with syphilis have lower delta13Ccol values than individuals without the disease; the observed difference between the two groups is about 0.3-0.4, which is relatively small but still meaningful. However, no difference between delta15Ncol values of the two groups has been noticed. CONCLUSIONS: Either diets prescribed by physicians to syphilitic patients or nutritional stress caused by cyclic appetite disturbance due to the disease itself or the administered medical treatment appeared to be possible explanations of the observed isotopic pattern. Overall, the response of the two isotopic proxies could argue for relatively limited nutritional restrictions. SIGNIFICANCE: This is the first study examining bone collagen isotopic response to syphilis based on clinically documented human skeletal materials. LIMITATIONS: The sample sizes are relatively small and cautiousness must be taken regarding the interpretations of the data. SUGGESTIONS FOR FURTHER RESEARCH: Compound-specific stable isotope investigations and analysis of mercury content could be helpful to better understand the observed isotopic effects.

Název v anglickém jazyce

An isotopic case study of individuals with syphilis from the pathological-anatomical reference collection of the national museum in Prague (Czech Republic, 19th century A.D.)

Popis výsledku anglicky

OBJECTIVE: This paper aims at investigating the possible existence of isotopic offsets in delta13Ccol and delta15Ncol values in relation to tertiary syphilis. MATERIAL: Based on materials from the 19th c. A.D. deriving from the pathological-anatomical reference collection (the Jedlicka collection) of the National Museum in Prague (Czech Republic), a comparative approach of ten individuals with syphilis and nine without the disease was undertaken. METHODS: Bone powder samples were defatted according to the protocol of Liden et al. (1995). Bone collagen was extracted following the protocol of Bocherens et al. (1991). RESULTS: Our results show that individuals with syphilis have lower delta13Ccol values than individuals without the disease; the observed difference between the two groups is about 0.3-0.4, which is relatively small but still meaningful. However, no difference between delta15Ncol values of the two groups has been noticed. CONCLUSIONS: Either diets prescribed by physicians to syphilitic patients or nutritional stress caused by cyclic appetite disturbance due to the disease itself or the administered medical treatment appeared to be possible explanations of the observed isotopic pattern. Overall, the response of the two isotopic proxies could argue for relatively limited nutritional restrictions. SIGNIFICANCE: This is the first study examining bone collagen isotopic response to syphilis based on clinically documented human skeletal materials. LIMITATIONS: The sample sizes are relatively small and cautiousness must be taken regarding the interpretations of the data. SUGGESTIONS FOR FURTHER RESEARCH: Compound-specific stable isotope investigations and analysis of mercury content could be helpful to better understand the observed isotopic effects.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

60102 - Archaeology

Projekt

<a href="/cs/project/GA19-13265S" target="_blank" >GA19-13265S: Zpřesnění rekonstrukce stravy minulých populací na příkladu středověké Moravy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of Paleopathology

ISSN

1879-9817

e-ISSN

—

Svazek periodika

25

Číslo periodika v rámci svazku

Neuveden

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

46-55

Kód UT WoS článku

000472633000006

EID výsledku v databázi Scopus

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