Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): A prospective international multicenter study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F22%3AN0000006" target="_blank" >RIV/00023698:_____/22:N0000006 - isvavai.cz</a>
Výsledek na webu
<a href="https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.17235" target="_blank" >https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.17235</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/1471-0528.17235" target="_blank" >10.1111/1471-0528.17235</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): A prospective international multicenter study
Popis výsledku v původním jazyce
Objective To assess the diagnostic performance of preoperative application of the Enzian classification (cEnzian) using surgical findings as reference standard. Design A prospective international non-interventional study. Setting Twelve endometriosis centres in four European countries (Austria, Germany, Switzerland and Czech Republic). Population 1062 women with endometriosis surgery. Methods Extent of endometriosis was preoperatively classified using the cEnzian classification based on gynaecological examination and/or transvaginal ultrasound (TVS) and/or magnetic resonance imaging (MRI). After subsequent surgery, the surgeon classified the intraoperative findings using the Enzian classification. Main outcome measures Sensitivity, specificity, PPV, NPV, LR+, LR- and accuracy were calculated. Conditional frequencies of intraoperative Enzian codings and the corresponding 95% confidence intervals were computed for each preoperative coding and visualised in plots. Results Although overall consistency of cEnzian and Enzian was poor (35.14%, 95% confidence interval 32.26-38.03), high specificities and negative predictive values (NPVs) of the cEnzian compartments could be demonstrated. Looking at the individual parts of the Enzian classification, the poorest diagnostic performance was detected for compartment B and the highest PPVs were found for category 3 lesions (>3 cm), independent of the compartment. Conclusions Using the Enzian classification in a non-invasive setting is a useful tool providing us with an 'at a glance' summary of the diagnostic workup regarding deep endometriosis with high specificities and NPVs. An attempt to merge the two new endometriosis classification systems (#Enzian and AAGL 2021) seems reasonable taking into consideration the respective advantages of each other.
Název v anglickém jazyce
Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): A prospective international multicenter study
Popis výsledku anglicky
Objective To assess the diagnostic performance of preoperative application of the Enzian classification (cEnzian) using surgical findings as reference standard. Design A prospective international non-interventional study. Setting Twelve endometriosis centres in four European countries (Austria, Germany, Switzerland and Czech Republic). Population 1062 women with endometriosis surgery. Methods Extent of endometriosis was preoperatively classified using the cEnzian classification based on gynaecological examination and/or transvaginal ultrasound (TVS) and/or magnetic resonance imaging (MRI). After subsequent surgery, the surgeon classified the intraoperative findings using the Enzian classification. Main outcome measures Sensitivity, specificity, PPV, NPV, LR+, LR- and accuracy were calculated. Conditional frequencies of intraoperative Enzian codings and the corresponding 95% confidence intervals were computed for each preoperative coding and visualised in plots. Results Although overall consistency of cEnzian and Enzian was poor (35.14%, 95% confidence interval 32.26-38.03), high specificities and negative predictive values (NPVs) of the cEnzian compartments could be demonstrated. Looking at the individual parts of the Enzian classification, the poorest diagnostic performance was detected for compartment B and the highest PPVs were found for category 3 lesions (>3 cm), independent of the compartment. Conclusions Using the Enzian classification in a non-invasive setting is a useful tool providing us with an 'at a glance' summary of the diagnostic workup regarding deep endometriosis with high specificities and NPVs. An attempt to merge the two new endometriosis classification systems (#Enzian and AAGL 2021) seems reasonable taking into consideration the respective advantages of each other.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30214 - Obstetrics and gynaecology
Návaznosti výsledku
Projekt
—
Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
ISSN
1470-0328
e-ISSN
1471-0528
Svazek periodika
129
Číslo periodika v rámci svazku
12
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
10
Strana od-do
2052-2061
Kód UT WoS článku
000805611200001
EID výsledku v databázi Scopus
2-s2.0-85131177242