Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023698%3A_____%2F24%3AN0000020" target="_blank" >RIV/00023698:_____/24:N0000020 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43926709 RIV/00064173:_____/24:43926709

Výsledek na webu

<a href="https://pubmed.ncbi.nlm.nih.gov/38376549/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/38376549/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00192-024-05733-3" target="_blank" >10.1007/s00192-024-05733-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

Popis výsledku v původním jazyce

Introduction and HypothesisThe main risk factor for pelvic floor disorders is vaginal delivery, which may cause levator ani muscle (LAM) injury and denervation. LAM includes pubovisceral muscle (PVM, pubococcygeus), puborectalis muscle (PRM), and iliococcygeus muscle. We hypothesize that primiparous women with low pelvic floor muscle contraction have a reduced PVM cross-sectional area (CSA) compared to nulliparous women.Methods (Sample Size and Statistical Approaches)This single-centre prospective observational study compared healthy nulliparous (n = 40) to primiparous (n = 40) women after vaginal delivery without LAM avulsion and Oxford score <= 3. Demographics, questionnaires (ICIQ-UI-SF, OAB-Q-SF, PISQ-12), POP-Q, Oxford score, ultrasound measurements (minimal anteroposterior and lateral diameters, hiatal area, PRM thickness, levator-urethra gap) and magnetic resonance imaging (MRI)-PVM CSA were evaluated. Normality was tested, and an appropriate test was used to compare the groups. Power calculation suggested 40 participants per group.ResultsThe primiparous group was older, had a higher BMI, and their hiatal area on ultrasound at contraction was larger compared to the nulliparous group. The CSA of the left-sided PVM (1.15 +/- 0.50 cm2) was larger compared to the right side (1.03 +/- 0.50 cm2), p = 0.02 in nulliparous women. The PVM CSA of primiparous women with low Oxford score was reduced compared to nulliparous (0.87 +/- 0.30 versus 1.09 +/- 0.50 cm2, p = 0.006). The intra-rater reliability for PVM CSA had an ICC of 0.90 and inter-rater ICC of 0.77.ConclusionsPrimiparous women after vaginal delivery with low pelvic floor contraction force had reduced PVM CSA on MRI images compared to nulliparous women.

Název v anglickém jazyce

Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women

Popis výsledku anglicky

Introduction and HypothesisThe main risk factor for pelvic floor disorders is vaginal delivery, which may cause levator ani muscle (LAM) injury and denervation. LAM includes pubovisceral muscle (PVM, pubococcygeus), puborectalis muscle (PRM), and iliococcygeus muscle. We hypothesize that primiparous women with low pelvic floor muscle contraction have a reduced PVM cross-sectional area (CSA) compared to nulliparous women.Methods (Sample Size and Statistical Approaches)This single-centre prospective observational study compared healthy nulliparous (n = 40) to primiparous (n = 40) women after vaginal delivery without LAM avulsion and Oxford score <= 3. Demographics, questionnaires (ICIQ-UI-SF, OAB-Q-SF, PISQ-12), POP-Q, Oxford score, ultrasound measurements (minimal anteroposterior and lateral diameters, hiatal area, PRM thickness, levator-urethra gap) and magnetic resonance imaging (MRI)-PVM CSA were evaluated. Normality was tested, and an appropriate test was used to compare the groups. Power calculation suggested 40 participants per group.ResultsThe primiparous group was older, had a higher BMI, and their hiatal area on ultrasound at contraction was larger compared to the nulliparous group. The CSA of the left-sided PVM (1.15 +/- 0.50 cm2) was larger compared to the right side (1.03 +/- 0.50 cm2), p = 0.02 in nulliparous women. The PVM CSA of primiparous women with low Oxford score was reduced compared to nulliparous (0.87 +/- 0.30 versus 1.09 +/- 0.50 cm2, p = 0.006). The intra-rater reliability for PVM CSA had an ICC of 0.90 and inter-rater ICC of 0.77.ConclusionsPrimiparous women after vaginal delivery with low pelvic floor contraction force had reduced PVM CSA on MRI images compared to nulliparous women.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

<a href="/cs/project/EF19_073%2F0016935" target="_blank" >EF19_073/0016935: Grantová schémata na UK</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

INTERNATIONAL UROGYNECOLOGY JOURNAL

ISSN

0937-3462

e-ISSN

1433-3023

Svazek periodika

35

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

841-848

Kód UT WoS článku

001171727700003

EID výsledku v databázi Scopus

2-s2.0-85185330523