Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjogren's syndrome: an OMERACT reliability exercise

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023728%3A_____%2F22%3AN0000016" target="_blank" >RIV/00023728:_____/22:N0000016 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1093/rheumatology/keab876" target="_blank" >https://doi.org/10.1093/rheumatology/keab876</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/rheumatology/keab876" target="_blank" >10.1093/rheumatology/keab876</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjogren's syndrome: an OMERACT reliability exercise

Popis výsledku v původním jazyce

Objective The aim of this exercise from the OMERACT Ultrasound subgroup on Sjogren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjogren's syndrome (pSS). Methods Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. Results The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. Conclusion The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.

Název v anglickém jazyce

Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjogren's syndrome: an OMERACT reliability exercise

Popis výsledku anglicky

Objective The aim of this exercise from the OMERACT Ultrasound subgroup on Sjogren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjogren's syndrome (pSS). Methods Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. Results The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. Conclusion The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30226 - Rheumatology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Rheumatology (Oxford)

ISSN

1462-0324

e-ISSN

1462-0332

Svazek periodika

61

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

3341-3350

Kód UT WoS článku

000789309500001

EID výsledku v databázi Scopus

2-s2.0-85135596590