Notes to the light microscopic morphology of the nucleolus in progenitors and mature cells of human leukemic granulocytic lineage

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Notes to the light microscopic morphology of the nucleolus in progenitors and mature cells of human leukemic granulocytic lineage

Popis výsledku v původním jazyce

The leukemic granulocytic cell lineage represents a very convenient model for studies on the nucleolar morphology in progenitor or mature cells. Diagnostic peripheral blood and bone marrow smears of patients suffering from chronic myelocytic leukemia possessed a satisfactory number of cells in early as well as advanced differentiation and maturation steps that were easily identified. Moreover, granulocytic progenitors were also cultured in established cell cultures originated from leukemic patients. Simple methods for the RNA visualization facilitated to visualize not only large but also very small nucleoli. Sites of the nucleolar RNA transcription - nucleolar fibrillar centers - in single cells were visualized by cytochemical reactions for main nucleolar proteins

Název v anglickém jazyce

Notes to the light microscopic morphology of the nucleolus in progenitors and mature cells of human leukemic granulocytic lineage

Popis výsledku anglicky

The leukemic granulocytic cell lineage represents a very convenient model for studies on the nucleolar morphology in progenitor or mature cells. Diagnostic peripheral blood and bone marrow smears of patients suffering from chronic myelocytic leukemia possessed a satisfactory number of cells in early as well as advanced differentiation and maturation steps that were easily identified. Moreover, granulocytic progenitors were also cultured in established cell cultures originated from leukemic patients. Simple methods for the RNA visualization facilitated to visualize not only large but also very small nucleoli. Sites of the nucleolar RNA transcription - nucleolar fibrillar centers - in single cells were visualized by cytochemical reactions for main nucleolar proteins

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30205 - Hematology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Advances in medicine and biology: vol. 156

ISBN

978-1-53616-690-3

Počet stran výsledku

15

Strana od-do

1-15

Počet stran knihy

150

Název nakladatele

New York

Místo vydání

New York

Kód UT WoS kapitoly

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