RNA concentration and content in the nucleoli and cytoplasmic rim in differentiating lymphocytes of patients suffering from B chronic lymphocytic leukaemia: a cytochemical note

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F22%3A00013457" target="_blank" >RIV/00023736:_____/22:00013457 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/22:10449159 RIV/00216208:11110/22:10449159

Výsledek na webu

<a href="https://fb.cuni.cz/file/6213/fb2022a0005.pdf" target="_blank" >https://fb.cuni.cz/file/6213/fb2022a0005.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

RNA concentration and content in the nucleoli and cytoplasmic rim in differentiating lymphocytes of patients suffering from B chronic lymphocytic leukaemia: a cytochemical note

Popis výsledku v původním jazyce

Nucleolar RNA optical density (concentration) measurements at the single cell level indicated that differentiation of lymphocytes is accompanied by a slightly decreased nucleolar RNA concentration in contrast to the cytoplasmic rim around the nucleus. On the other hand, the nucleolar size was markedly reduced and the cytoplasmic rim surrounding the nucleus was reduced only weakly. Concerning the calculated rough estimate of the RNA content, the differentiation induced its larger decrease in the nucleoli than in the cytoplasmic rim. These observations indicated that the nucleolar RNA concentration and RNA content together with the nucleolar morphology are more sensitive markers of the differentiation process than the RNA concentration and content in the cytoplasm.

Název v anglickém jazyce

RNA concentration and content in the nucleoli and cytoplasmic rim in differentiating lymphocytes of patients suffering from B chronic lymphocytic leukaemia: a cytochemical note

Popis výsledku anglicky

Nucleolar RNA optical density (concentration) measurements at the single cell level indicated that differentiation of lymphocytes is accompanied by a slightly decreased nucleolar RNA concentration in contrast to the cytoplasmic rim around the nucleus. On the other hand, the nucleolar size was markedly reduced and the cytoplasmic rim surrounding the nucleus was reduced only weakly. Concerning the calculated rough estimate of the RNA content, the differentiation induced its larger decrease in the nucleoli than in the cytoplasmic rim. These observations indicated that the nucleolar RNA concentration and RNA content together with the nucleolar morphology are more sensitive markers of the differentiation process than the RNA concentration and content in the cytoplasm.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30205 - Hematology

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia biologica

ISSN

0015-5500

e-ISSN

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Svazek periodika

68

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

40-44

Kód UT WoS článku

000866490600005

EID výsledku v databázi Scopus

2-s2.0-85139320566