Decoding the historical tale: COVID-19 impact on haematological malignancy patients: EPICOVIDEHA insights from 2020 to 2022

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F24%3A00013648" target="_blank" >RIV/00023736:_____/24:00013648 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00137430 RIV/65269705:_____/24:00080457 RIV/00179906:_____/24:10484297 RIV/00064173:_____/24:43927649 a 2 dalších

Výsledek na webu

<a href="https://doi.org/10.1016/j.eclinm.2024.102553" target="_blank" >https://doi.org/10.1016/j.eclinm.2024.102553</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.eclinm.2024.102553" target="_blank" >10.1016/j.eclinm.2024.102553</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Decoding the historical tale: COVID-19 impact on haematological malignancy patients: EPICOVIDEHA insights from 2020 to 2022

Popis výsledku v původním jazyce

The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. While interventions like vaccines, targeted antivirals, and monoclonal antibodies have been effective for the general population, their benefits for these patients may not be as pronounced. The EPICOVIDEHA registry (National Clinical Trials Identifier, NCT04733729) gathers COVID-19 data from hematological malignancy patients since the pandemic's start worldwide. It spans various global locations, allowing comprehensive analysis over the first three years (2020–2022). Patients with hematological malignancies still face elevated risks, despite reductions in critical infections and overall mortality rates over time. Hospitalization, especially in ICUs, remains a significant concern. The study underscores the importance of vaccination and the timing of COVID-19 exposure in 2022 for enhanced survival in this patient group. Ongoing monitoring and targeted interventions are essential to support this vulnerable population, emphasizing the critical role of timely diagnosis and prompt treatment in preventing severe COVID-19 cases.

Název v anglickém jazyce

Decoding the historical tale: COVID-19 impact on haematological malignancy patients: EPICOVIDEHA insights from 2020 to 2022

Popis výsledku anglicky

The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. While interventions like vaccines, targeted antivirals, and monoclonal antibodies have been effective for the general population, their benefits for these patients may not be as pronounced. The EPICOVIDEHA registry (National Clinical Trials Identifier, NCT04733729) gathers COVID-19 data from hematological malignancy patients since the pandemic's start worldwide. It spans various global locations, allowing comprehensive analysis over the first three years (2020–2022). Patients with hematological malignancies still face elevated risks, despite reductions in critical infections and overall mortality rates over time. Hospitalization, especially in ICUs, remains a significant concern. The study underscores the importance of vaccination and the timing of COVID-19 exposure in 2022 for enhanced survival in this patient group. Ongoing monitoring and targeted interventions are essential to support this vulnerable population, emphasizing the critical role of timely diagnosis and prompt treatment in preventing severe COVID-19 cases.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30205 - Hematology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

EClinical medicine

ISSN

2589-5370

e-ISSN

—

Svazek periodika

71

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

20

Strana od-do

"art. no. 102553"

Kód UT WoS článku

001311054400001

EID výsledku v databázi Scopus

2-s2.0-85188194524