Social interaction deficits in schizophrenia-spectrum disorders and pharmacologic intervention

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F09%3A00001023" target="_blank" >RIV/00023752:_____/09:00001023 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Social interaction deficits in schizophrenia-spectrum disorders and pharmacologic intervention

Popis výsledku v původním jazyce

Disturbances of social interaction in people suffering from major psychiatric illnesses have attracted concerns from clinicians, researchers, and healthcare administrators, as these deficits are a major determinant of outcome for patients. Impaired social abilities in schizophrenia-spectrum disorders and autism are thought to be partly attributable to specific aspects of symptomatology, such as negative symptoms (blunt affect, social withdrawal, anhedonia) and disturbances of several domains of cognitive function, e.g. verbal memory, working memory, attention/vigilance, and information processing. We recently found that severity of social cognition deficits is correlated with decreased concentrations of essential polyunsaturated fatty acids in the erythrocyte membrane in subjects with schizophrenia. Psychotropic drugs acting on monoamine receptors, such as serotonin (5-HT)-5HT1A, and 5-HT2A receptors, have been shown to improve social behavior and cognitive function in rodents. For exa

Název v anglickém jazyce

Social interaction deficits in schizophrenia-spectrum disorders and pharmacologic intervention

Popis výsledku anglicky

Disturbances of social interaction in people suffering from major psychiatric illnesses have attracted concerns from clinicians, researchers, and healthcare administrators, as these deficits are a major determinant of outcome for patients. Impaired social abilities in schizophrenia-spectrum disorders and autism are thought to be partly attributable to specific aspects of symptomatology, such as negative symptoms (blunt affect, social withdrawal, anhedonia) and disturbances of several domains of cognitive function, e.g. verbal memory, working memory, attention/vigilance, and information processing. We recently found that severity of social cognition deficits is correlated with decreased concentrations of essential polyunsaturated fatty acids in the erythrocyte membrane in subjects with schizophrenia. Psychotropic drugs acting on monoamine receptors, such as serotonin (5-HT)-5HT1A, and 5-HT2A receptors, have been shown to improve social behavior and cognitive function in rodents. For exa

Druh

C - Kapitola v odborné knize

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Handbook of Social Interactions in the 21st Century

ISBN

978-1-60692-860-8

Počet stran výsledku

8

Strana od-do

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Počet stran knihy

397

Název nakladatele

Nova Science Publishers, Inc.

Místo vydání

New York

Kód UT WoS kapitoly

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