Predictors of the successful treatment of heroin addiction and other illicit opioids. Systematic review

Kód výsledku v IS VaVaI

RIV/00023752:_____/18:43919068 - isvavai.cz

Výsledek na webu

https://www.addictology.cz/wp-content/uploads/2019/02/06_orlikova.pdf

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Predictors of the successful treatment of heroin addiction and other illicit opioids. Systematic review

Popis výsledku v původním jazyce

Background: Dependence on heroin (and other illicit opioids) is a serious health and social problem. In the Czech Republic, there are an estimated 4,500 problem heroin users and 7,100 users of diverted buprenorphine (especially Subutex®). Users of heroin and other opioids are the second largest group of drug users in treatment. The treatment of opioid dependence involves psychosocial (abstinence-based) and/or pharmacological (substitution treatment) interventions. Methods: Systematic review. Specialised databases (ScienceDirect, Scopus, Cochrane Database) and other sources (Medvik) were searched for both international and Czech scientific literature on the treatment of addiction to heroin (or other illegal opiates) and factors influencing its outcomes. The search focused on texts published between 2000 and 2017. Conclusions: The basic predictors that have a positive effect on the success of the treatment of opiate addiction are the length of treatment and specific sociodemographic (such as age at entry to treatment) and psychological characteristics. While psychiatric comorbidity is generally a risk factor, some studies found patients with concurrent psychiatric diagnoses (especially depression) showing higher treatment retention rates. The pressure of the client’s conflicts with the law also improves retention in treatment and its overall outcome. Another positive predictor is a family situation with no major conflicts and the absence of addiction issues among patients’ family members and partners. Substitution treatment was found to show higher treatment retention rates than abstinence-based psychosocial therapy. The success of substitution treatment is associated with higher doses (whether of methadone or buprenorphine – as the most common substitution medicines), psychosocial support during treatment, but without excessive pressure on the client to change their lifestyle, and good relationships with the service staff. Taking other drugs during treatment was found to cause a deterioration of the outcomes. Users of opioids other than heroin and non-injecting users seem to achieve better treatment outcomes.

Název v anglickém jazyce

Predictors of the successful treatment of heroin addiction and other illicit opioids. Systematic review

Popis výsledku anglicky

Background: Dependence on heroin (and other illicit opioids) is a serious health and social problem. In the Czech Republic, there are an estimated 4,500 problem heroin users and 7,100 users of diverted buprenorphine (especially Subutex®). Users of heroin and other opioids are the second largest group of drug users in treatment. The treatment of opioid dependence involves psychosocial (abstinence-based) and/or pharmacological (substitution treatment) interventions. Methods: Systematic review. Specialised databases (ScienceDirect, Scopus, Cochrane Database) and other sources (Medvik) were searched for both international and Czech scientific literature on the treatment of addiction to heroin (or other illegal opiates) and factors influencing its outcomes. The search focused on texts published between 2000 and 2017. Conclusions: The basic predictors that have a positive effect on the success of the treatment of opiate addiction are the length of treatment and specific sociodemographic (such as age at entry to treatment) and psychological characteristics. While psychiatric comorbidity is generally a risk factor, some studies found patients with concurrent psychiatric diagnoses (especially depression) showing higher treatment retention rates. The pressure of the client’s conflicts with the law also improves retention in treatment and its overall outcome. Another positive predictor is a family situation with no major conflicts and the absence of addiction issues among patients’ family members and partners. Substitution treatment was found to show higher treatment retention rates than abstinence-based psychosocial therapy. The success of substitution treatment is associated with higher doses (whether of methadone or buprenorphine – as the most common substitution medicines), psychosocial support during treatment, but without excessive pressure on the client to change their lifestyle, and good relationships with the service staff. Taking other drugs during treatment was found to cause a deterioration of the outcomes. Users of opioids other than heroin and non-injecting users seem to achieve better treatment outcomes.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

50102 - Psychology, special (including therapy for learning, speech, hearing, visual and other physical and mental disabilities);

Projekt

LO1611: Udržitelnost pro Národní ústav duševního zdraví

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Adiktologie

ISSN

1213-3841

e-ISSN

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Svazek periodika

2018

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

12

Strana od-do

105-116

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-85073770581