Methods for animal brain mapping

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F18%3A43919485" target="_blank" >RIV/00023752:_____/18:43919485 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/18:43917128

Výsledek na webu

<a href="https://www.radioeng.cz/fulltexts/2018/18_03_0806_0812.pdf" target="_blank" >https://www.radioeng.cz/fulltexts/2018/18_03_0806_0812.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.13164/re.2018.0806" target="_blank" >10.13164/re.2018.0806</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Methods for animal brain mapping

Popis výsledku v původním jazyce

Measurements of brain electrical activity in animals are essential for the validation of the pharmaco-effect of drugs. The way to evaluate these recordings should be comparable to that of EEG in humans. Methods that visualize the results of the measured EEG recording include brain mapping in two-dimensional or three-dimensional space. The most commonly used methods of interpolation techniques in humans are spherical splines and 3D splines. We measured nine brains of Wistar rats and compared them with a brain model from the atlas (Brain Atlas Reconstructor, BAR). We validated the brain model of Wistar rat for future use. We implemented a module in MATLAB 2015a for brain mapping, specifically, we implemented algorithms for spherical and 3D spline mapping. The root mean square error of the spherical spline method is 0.5943 in the case of testing signal and 0.6291/0.6388 in the case of real data estimation. The root mean square error of the 3D spline method is 0.4334 in the case of testing signal and 0.0849/0.0768 in the case of real data estimation. Our results show that the 3D spline method with the projection on sphere gives significantly better 3D potential map than spherical splines.

Název v anglickém jazyce

Methods for animal brain mapping

Popis výsledku anglicky

Measurements of brain electrical activity in animals are essential for the validation of the pharmaco-effect of drugs. The way to evaluate these recordings should be comparable to that of EEG in humans. Methods that visualize the results of the measured EEG recording include brain mapping in two-dimensional or three-dimensional space. The most commonly used methods of interpolation techniques in humans are spherical splines and 3D splines. We measured nine brains of Wistar rats and compared them with a brain model from the atlas (Brain Atlas Reconstructor, BAR). We validated the brain model of Wistar rat for future use. We implemented a module in MATLAB 2015a for brain mapping, specifically, we implemented algorithms for spherical and 3D spline mapping. The root mean square error of the spherical spline method is 0.5943 in the case of testing signal and 0.6291/0.6388 in the case of real data estimation. The root mean square error of the 3D spline method is 0.4334 in the case of testing signal and 0.0849/0.0768 in the case of real data estimation. Our results show that the 3D spline method with the projection on sphere gives significantly better 3D potential map than spherical splines.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

<a href="/cs/project/LO1611" target="_blank" >LO1611: Udržitelnost pro Národní ústav duševního zdraví</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Radioengineering

ISSN

1210-2512

e-ISSN

—

Svazek periodika

27

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

806-812

Kód UT WoS článku

000444598500023

EID výsledku v databázi Scopus

2-s2.0-85053330335