Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F24%3A43921341" target="_blank" >RIV/00023752:_____/24:43921341 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/24:10482811 RIV/00216208:11150/24:10482811 RIV/00179906:_____/24:10482811

Výsledek na webu

<a href="https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/contribution-of-severe-mental-disorders-to-fatally-harmful-effects-of-physical-disorders-national-cohort-study/989B99917BC7327F1AF8696C17EEEB92" target="_blank" >https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/contribution-of-severe-mental-disorders-to-fatally-harmful-effects-of-physical-disorders-national-cohort-study/989B99917BC7327F1AF8696C17EEEB92</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1192/bjp.2024.110" target="_blank" >10.1192/bjp.2024.110</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study

Popis výsledku v původním jazyce

Background It remains unknown whether severe mental disorders contribute to fatally harmful effects of physical illness.Aims To investigate the risk of all-cause death and loss of life-years following the onset of a wide range of physical health conditions in people with severe mental disorders compared with matched counterparts who had only these physical health conditions, and to assess whether these associations can be fully explained by this patient group having more clinically recorded physical illness.Method Using Czech national in-patient register data, we identified individuals with 28 physical health conditions recorded between 1999 and 2017, separately for each condition. In these people, we identified individuals who had severe mental disorders recorded before the physical health condition and exactly matched them with up to five counterparts who had no recorded prior severe mental disorders. We estimated the risk of all-cause death and lost life-years following each of the physical health conditions in people with pre-existing severe mental disorders compared with matched counterparts without severe mental disorders.Results People with severe mental disorders had an elevated risk of all-cause death following the onset of 7 out of 9 broadly defined and 14 out of 19 specific physical health conditions. People with severe mental disorders lost additional life-years following the onset of 8 out 9 broadly defined and 13 out of 19 specific physical health conditions. The vast majority of results remained robust after considering the potentially confounding role of somatic multimorbidity and other clinical and sociodemographic factors.Conclusions A wide range of physical illnesses are more likely to result in all-cause death in people with pre-existing severe mental disorders. This premature mortality cannot be fully explained by having more clinically recorded physical illness, suggesting that physical disorders are more likely to be fatally harmful in this patient group.

Název v anglickém jazyce

Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study

Popis výsledku anglicky

Background It remains unknown whether severe mental disorders contribute to fatally harmful effects of physical illness.Aims To investigate the risk of all-cause death and loss of life-years following the onset of a wide range of physical health conditions in people with severe mental disorders compared with matched counterparts who had only these physical health conditions, and to assess whether these associations can be fully explained by this patient group having more clinically recorded physical illness.Method Using Czech national in-patient register data, we identified individuals with 28 physical health conditions recorded between 1999 and 2017, separately for each condition. In these people, we identified individuals who had severe mental disorders recorded before the physical health condition and exactly matched them with up to five counterparts who had no recorded prior severe mental disorders. We estimated the risk of all-cause death and lost life-years following each of the physical health conditions in people with pre-existing severe mental disorders compared with matched counterparts without severe mental disorders.Results People with severe mental disorders had an elevated risk of all-cause death following the onset of 7 out of 9 broadly defined and 14 out of 19 specific physical health conditions. People with severe mental disorders lost additional life-years following the onset of 8 out 9 broadly defined and 13 out of 19 specific physical health conditions. The vast majority of results remained robust after considering the potentially confounding role of somatic multimorbidity and other clinical and sociodemographic factors.Conclusions A wide range of physical illnesses are more likely to result in all-cause death in people with pre-existing severe mental disorders. This premature mortality cannot be fully explained by having more clinically recorded physical illness, suggesting that physical disorders are more likely to be fatally harmful in this patient group.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

British Journal of Psychiatry

ISSN

0007-1250

e-ISSN

1472-1465

Svazek periodika

225

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

436-445

Kód UT WoS článku

001286250000001

EID výsledku v databázi Scopus

2-s2.0-85200943249