High-frequency neurostimulation of the right inferior parietal cortex alters the sense of agency: Results from tACS/tRNS and rTMS-EEG studies
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023752%3A_____%2F25%3A43921678" target="_blank" >RIV/00023752:_____/25:43921678 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/68407700:21230/25:00388164 RIV/68407700:21460/25:00388164 RIV/00216208:11120/25:43928644
Výsledek na webu
<a href="https://www.sciencedirect.com/science/article/pii/S1053811925003672?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1053811925003672?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.neuroimage.2025.121364" target="_blank" >10.1016/j.neuroimage.2025.121364</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
High-frequency neurostimulation of the right inferior parietal cortex alters the sense of agency: Results from tACS/tRNS and rTMS-EEG studies
Popis výsledku v původním jazyce
Background: Sense of agency (SoA) is the subjective experience of causing and controlling one's actions. Recent studies have linked SoA to gamma-band oscillations in the right inferior parietal lobule (IPL) and suggest that it can be modulated through external interventions using neurostimulation techniques. Objective: This study aims to provide evidence for a causal role of the right IPL in SoA using multiple noninvasive brain stimulation methods (NIBS), electroencephalography (EEG), and a feedback manipulation task. Methods: In two experiments, we investigated the effect of gamma band (60 Hz) transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS), low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS), and high-frequency (10 Hz, 20 Hz) rTMS over the right IPL. Results: As anticipated, gamma band tACS and high-frequency rTMS had distinct effects on SoA. Gamma band tACS enhanced the detection of non-self agency, while high-frequency rTMS impaired this capacity and reduced the overall SoA. EEG spectral analysis confirmed the impact of stimulation on the right IPL and highlighted the role of beta band oscillations. Conclusion: Using the largest subject pool to date, our study provides causal evidence for the crucial role of the right IPL in processing SoA, particularly in detecting non-self agency arising from real-time sensorimotor mismatch comparison. Our findings suggest that external stimulation affects the comparator mechanism, rather than introducing prediction errors as previously proposed, and support the view that the right IPL is more closely associated with the implicit feeling of agency rather than with higher cognitive processes.
Název v anglickém jazyce
High-frequency neurostimulation of the right inferior parietal cortex alters the sense of agency: Results from tACS/tRNS and rTMS-EEG studies
Popis výsledku anglicky
Background: Sense of agency (SoA) is the subjective experience of causing and controlling one's actions. Recent studies have linked SoA to gamma-band oscillations in the right inferior parietal lobule (IPL) and suggest that it can be modulated through external interventions using neurostimulation techniques. Objective: This study aims to provide evidence for a causal role of the right IPL in SoA using multiple noninvasive brain stimulation methods (NIBS), electroencephalography (EEG), and a feedback manipulation task. Methods: In two experiments, we investigated the effect of gamma band (60 Hz) transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS), low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS), and high-frequency (10 Hz, 20 Hz) rTMS over the right IPL. Results: As anticipated, gamma band tACS and high-frequency rTMS had distinct effects on SoA. Gamma band tACS enhanced the detection of non-self agency, while high-frequency rTMS impaired this capacity and reduced the overall SoA. EEG spectral analysis confirmed the impact of stimulation on the right IPL and highlighted the role of beta band oscillations. Conclusion: Using the largest subject pool to date, our study provides causal evidence for the crucial role of the right IPL in processing SoA, particularly in detecting non-self agency arising from real-time sensorimotor mismatch comparison. Our findings suggest that external stimulation affects the comparator mechanism, rather than introducing prediction errors as previously proposed, and support the view that the right IPL is more closely associated with the implicit feeling of agency rather than with higher cognitive processes.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30103 - Neurosciences (including psychophysiology)
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2025
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Neuroimage
ISSN
1053-8119
e-ISSN
1095-9572
Svazek periodika
318
Číslo periodika v rámci svazku
"Article Number 121364"
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
12
Strana od-do
1-12
Kód UT WoS článku
001541118900001
EID výsledku v databázi Scopus
2-s2.0-105011168994