Vitamin D: Current Challenges between the Laboratory and Clinical Practice

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023761%3A_____%2F21%3AN0000015" target="_blank" >RIV/00023761:_____/21:N0000015 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/2072-6643/13/6/1758/htm" target="_blank" >https://www.mdpi.com/2072-6643/13/6/1758/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/nu13061758" target="_blank" >10.3390/nu13061758</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Vitamin D: Current Challenges between the Laboratory and Clinical Practice

Popis výsledku v původním jazyce

Vitamin D is a micronutrient with pleiotropic effects in humans. Due to sedentary lifestyles and increasing time spent indoors, a growing body of research is revealing that vitamin D deficiency is a global problem. Despite the routine measurement of vitamin D in clinical laboratories and many years of efforts, methods of vitamin D analysis have yet to be standardized and are burdened with significant difficulties. This review summarizes several key analytical and clinical challenges that accompany the current methods for measuring vitamin D. According to an external quality assessment, methods and laboratories still produce a high degree of variability. Structurally similar metabolites are a source of significant interference. Furthermore, there is still no consensus on the normal values of vitamin D in a healthy population. These and other problems discussed herein can be a source of inconsistency in the results of research studies.

Název v anglickém jazyce

Vitamin D: Current Challenges between the Laboratory and Clinical Practice

Popis výsledku anglicky

Vitamin D is a micronutrient with pleiotropic effects in humans. Due to sedentary lifestyles and increasing time spent indoors, a growing body of research is revealing that vitamin D deficiency is a global problem. Despite the routine measurement of vitamin D in clinical laboratories and many years of efforts, methods of vitamin D analysis have yet to be standardized and are burdened with significant difficulties. This review summarizes several key analytical and clinical challenges that accompany the current methods for measuring vitamin D. According to an external quality assessment, methods and laboratories still produce a high degree of variability. Structurally similar metabolites are a source of significant interference. Furthermore, there is still no consensus on the normal values of vitamin D in a healthy population. These and other problems discussed herein can be a source of inconsistency in the results of research studies.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30308 - Nutrition, Dietetics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

NUTRIENTS

ISSN

2072-6643

e-ISSN

2072-6643

Svazek periodika

13

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

15

Strana od-do

1758

Kód UT WoS článku

000666558700001

EID výsledku v databázi Scopus

2-s2.0-85105975449